MODY in Ukraine: genes, clinical phenotypes and treatment
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pediatric Endocrinology and Metabolism"
DOI: 10.1515/jpem-2017-0075
Abstract: Abstract Background: Maturity-onset diabetes of the young (MODY) has not been previously studied in Ukraine. We investigated the genetic etiology in a selected cohort of patients with diabetes diagnosed before 18 years of age, and… read more here.
Keywords: genes clinical; ukraine genes; clinical phenotypes; mody ukraine ... See more keywords
In vivo Environment Swiftly Restricts Human Pancreatic Progenitors Toward Mono-Hormonal Identity via a HNF1A/HNF4A Mechanism
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.00109
Abstract: Generating insulin-producing β-cells from human induced pluripotent stem cells is a promising cell replacement therapy for improving or curing insulin-dependent diabetes. The transplantation of end-stages differentiating cells into living hosts was demonstrated to improve β-cell… read more here.
Keywords: human pancreatic; vivo environment; hnf1a hnf4a; identity ... See more keywords