Articles with "hnf4 smad4" as a keyword



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A reinforcing HNF4-SMAD4 feed-forward module stabilizes enterocyte identity

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Published in 2019 at "Nature genetics"

DOI: 10.1038/s41588-019-0384-0

Abstract: BMP/SMAD signaling is a crucial regulator of intestinal differentiation1–4. However, the molecular underpinnings of the BMP pathway in this context are unknown. Here, we characterize the mechanism by which BMP/SMAD signaling drives enterocyte differentiation. We… read more here.

Keywords: hnf4 smad4; module; hnf4; stabilizes enterocyte ... See more keywords