Marein protects human nucleus pulposus cells against high glucose-induced injury and extracellular matrix degradation at least partly by inhibition of ROS/NF-κB pathway.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2019.106126
Abstract: Intervertebral disc degeneration (IDD), a major cause of discogenic low back pain, is a musculoskeletal disorder involving the apoptosis of nucleus pulposus cells (NPCs) and extracellular matrix (ECM) degradation. Marein is a major active flavonoid… read more here.
Keywords: hnpcs; degradation; induced injury; ecm degradation ... See more keywords
Anti-Zika virus RNAi in neural progenitor cells
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DOI: 10.1038/s41422-019-0158-3
Abstract: Zika virus (ZIKV), a flavivirus that is primarily transmitted by mosquitoes, can cause devastating microcephaly and other congenital syndromes in infants born to infected pregnant women. In a recent paper in Cell Research, Xu et… read more here.
Keywords: hnpcs; infection; zikv infection; zikv ... See more keywords
Substrate stiffness induced mechanotransduction regulates temporal evolution of human fetal neural progenitor cell phenotype, differentiation, and biomechanics.
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DOI: 10.1039/d0bm01349h
Abstract: While the mechanotransduction-induced fate of adult neural stem/progenitor cells (NPCs) is relatively known, how substrate stiffness regulates the temporal evolution of the biomechanics and phenotype of developmentally relevant human fetal NPCs (hNPCs) and their mechanosensing… read more here.
Keywords: hnpcs; biomechanics; temporal evolution; cell ... See more keywords