The RNA N6‐methyladenosine modulator HNRNPA2B1 is involved in the development of non‐small cell lung cancer
Sign Up to like & getrecommendations! Published in 2021 at "Clinical and Experimental Pharmacology and Physiology"
DOI: 10.1111/1440-1681.13608
Abstract: The key N6 methyladenosine (m6A) RNA methylation regulator is associated with multiple tumour progression. However, the m6A‐associated regulators that influence non‐small cell lung cancer (NSCLC) development have not been fully clarified. The m6A regulator expression… read more here.
Keywords: cancer; development; hnrnpa2b1; small cell ... See more keywords
Nuclear hnRNPA2B1 initiates and amplifies the innate immune response to DNA viruses
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DOI: 10.1126/science.aav0758
Abstract: A nuclear sensor of viral DNA? A signaling pathway in eukaryotes known as cGAS–STING recognizes the presence of cytosolic DNA, which alerts the immune system to viral infection or cellular damage. However, the majority of… read more here.
Keywords: dna; infection; hnrnpa2b1; virus ... See more keywords
HNRNPA2B1 Demonstrates Diagnostic and Prognostic Values Based on Pan-Cancer Analyses
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/9867660
Abstract: Some studies have suggested heterogeneous nuclear ribonucleoprotein A2/B1 (HNRNPA2B1) to be a promoter in cancer development. Nonetheless, no detailed pan-cancer investigation has been reported. Thus, this study explored the possible oncogenic role of HNRNPA2B1, such… read more here.
Keywords: pan cancer; hnrnpa2b1; hnrnpa2b1 demonstrates; cancer ... See more keywords
SUN-009 N(6)-Methyladenosine Reader HNRNPA2B1 Regulates Tamoxifen-Sensitivity in Breast Cancer Cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the Endocrine Society"
DOI: 10.1210/js.2019-sun-009
Abstract: Abstract The RNA methylation reader Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRNPA2B1) is a reader of the N(6)-methyladenosine (m6A) mark in mRNA and primary-miRNAs, HNRNPA2B1 interacts directly with DGCR8 in the DROSHA complex to promote processing of… read more here.
Keywords: expression; methyladenosine; sun 009; hnrnpa2b1 ... See more keywords
Preclinical Evaluation of hnRNPA2B1 Antibody in Human Triple-Negative Breast Cancer MDA-MB-231 Cells via PET Imaging
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14081677
Abstract: Triple-negative breast cancer (TNBC) does not express estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2. Because TNBC lacks the expression of commonly targeted receptors, it is challenging to develop a new imaging… read more here.
Keywords: triple negative; hnrnpa2b1; tumor; negative breast ... See more keywords