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   Articles with "hnrnpk" as a keyword



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SGLT2 promotes pancreatic cancer progression by activating the Hippo signaling pathway via the hnRNPK-YAP1 axis.

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recommendations! Published in 2021 at "Cancer letters"

DOI: 10.1016/j.canlet.2021.07.035

Abstract: SGLT2 is overexpressed in various cancers, including pancreatic cancer. However, the mechanisms underlying the tumorigenic effects of SGLT2 in pancreatic cancer remain unclear. In this study, we demonstrated that SGLT2 inhibition significantly suppressed the growth… read more here.

Keywords: sglt2 promotes; hippo signaling; pancreatic cancer; hnrnpk ... See more keywords
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FGD5-AS1 facilitates glioblastoma progression by activation of Wnt/β-catenin signaling via regulating miR-129-5p/HNRNPK axis.

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recommendations! Published in 2020 at "Life sciences"

DOI: 10.1016/j.lfs.2020.117998

Abstract: AIMS Accumulating evidence elucidates the biological significance of long non-coding RNA (lncRNAs) in tumorigenesis and development. FGD5 antisense RNA 1 (FGD5-AS1) was previously revealed as an oncogene in several types of malignancies. However, the roles… read more here.

Keywords: mir 129; fgd5 as1; as1; hnrnpk ... See more keywords
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hnRNPK-regulated PTOV1-AS1 modulates heme oxygenase-1 expression via miR-1207-5p

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recommendations! Published in 2017 at "BMB Reports"

DOI: 10.5483/bmbrep.2017.50.4.024

Abstract: Antisense transcripts were initially identified as transcriptional noise, but have since been reported to play an important role in the quality control of miRNA functions. In this report, we tested the hypothesis that heterogeneous nuclear… read more here.

Keywords: hnrnpk; mir 1207; expression; ptov1 as1 ... See more keywords
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Peroxiredoxin 5 regulates osteogenic differentiation through interaction with hnRNPK during bone regeneration

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recommendations! Published in 2023 at "eLife"

DOI: 10.7554/elife.80122

Abstract: Peroxiredoxin 5 (Prdx5) is involved in pathophysiological regulation via the stress-induced cellular response. However, its function in the bone remains largely unknown. Here, we show that Prdx5 is involved in osteoclast and osteoblast differentiation, resulting… read more here.

Keywords: bone; hnrnpk; peroxiredoxin regulates; differentiation ... See more keywords