Articles with "hnrnpl" as a keyword



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HNRNPL Circularizes ARHGAP35 to Produce an Oncogenic Protein

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Published in 2021 at "Advanced Science"

DOI: 10.1002/advs.202001701

Abstract: Abstract Circular RNAs (circRNAs) are an intriguing class of widely prevalent endogenous RNAs, the vast majority of which have not been characterized functionally. Here, we identified a novel oncogenic circRNA originating from the back‐splicing of… read more here.

Keywords: protein; protein hnrnpl; hnrnpl circularizes; hnrnpl ... See more keywords
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The Long Noncoding RNA Cancer Susceptibility 9 and RNA Binding Protein Heterogeneous Nuclear Ribonucleoprotein L Form a Complex and Coregulate Genes Linked to AKT Signaling

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Published in 2018 at "Hepatology"

DOI: 10.1002/hep.30102

Abstract: The identification of viability‐associated long noncoding RNAs (lncRNAs) might be a promising rationale for new therapeutic approaches in liver cancer. Here, we applied an RNA interference screening approach in hepatocellular carcinoma (HCC) cell lines to… read more here.

Keywords: hcc; akt signaling; viability; hnrnpl ... See more keywords
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Enhanced myogenesis through lncFAM-mediated recruitment of HNRNPL to the MYBPC2 promoter.

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Published in 2022 at "Nucleic acids research"

DOI: 10.1093/nar/gkac1174

Abstract: The mammalian transcriptome comprises a vast family of long noncoding (lnc)RNAs implicated in physiologic processes such as myogenesis, through which muscle forms during embryonic development and regenerates in the adult. However, the specific molecular mechanisms… read more here.

Keywords: mybpc2; promoter; lncfam; hnrnpl ... See more keywords
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HnRNPL promotes Wilms tumor progression by regulating the p53 and Bcl2 pathways

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Published in 2019 at "OncoTargets and therapy"

DOI: 10.2147/ott.s203046

Abstract: Background: Wilms tumor (WT) is the most common renal tumor in children with diffusely anaplastic or unfavorable histology, indicative of a poor prognosis. Heterogeneous nuclear ribonucleoprotein L (hnRNPL) is an RNA-binding protein (RBP) and a… read more here.

Keywords: p53; wilms tumor; p53 bcl2; hnrnpl ... See more keywords