Articles with "hnsc" as a keyword



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Identification of SLC2A3 as a prognostic indicator correlated with the NF-κB/EMT axis and immune response in head and neck squamous cell carcinoma

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Published in 2023 at "Channels"

DOI: 10.1080/19336950.2023.2208928

Abstract: ABSTRACT SLC2A3 is an important member of the glucose transporter superfamily. It has been recently suggested that upregulation of SLC2A3 is associated with poor survival and acts as a prognostic marker in a variety of… read more here.

Keywords: emt axis; cell; slc2a3; expression ... See more keywords
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Identification of the Potential Correlation between Tumor Protein 73 and Head and Neck Squamous Cell Carcinoma

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Published in 2022 at "Disease Markers"

DOI: 10.1155/2022/6410113

Abstract: Background Head and neck squamous cell carcinomas (HNSC) are common malignant tumors with a high occurrence and poor prognosis. Tumor protein P73 (TP73) plays an integral role in a wide range of human malignancies, but… read more here.

Keywords: head neck; squamous cell; tp73; neck squamous ... See more keywords
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Abstract A07: Improved prognosis of HPV-positive oropharyngeal cancers is associated with a suppression of TGF-β-mediated immune evasion

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Published in 2020 at "Clinical Cancer Research"

DOI: 10.1158/1557-3265.aacrahns19-a07

Abstract: Among head and neck squamous carcinoma (HNSC), human papilloma virus (HPV)-driven tumors are known to enjoy more favorable prognostic outcomes compared to non-HPV-driven disease. This is especially true of HPV-positive oropharyngeal squamous cell carcinoma (OPSCC),… read more here.

Keywords: positive oropharyngeal; prognosis; hpv positive; hnsc ... See more keywords
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Comparisons of Forecasting for Survival Outcome for Head and Neck Squamous Cell Carcinoma by using Machine Learning Models based on Multi-omics

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Published in 2022 at "Current Genomics"

DOI: 10.2174/1389202923666220204153744

Abstract: Background: Machine learning methods showed excellent predictive ability in a wide range of fields. For the survival of head and neck squamous cell carcinoma (HNSC), its multi-omics influence is crucial. This study attempts to establish… read more here.

Keywords: multi omics; machine learning; head neck; hnsc ... See more keywords
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Cuproptosis-related LncRNAs are correlated with immunity and predict prognosis in HNSC independent of TMB

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Published in 2023 at "Frontiers in Genetics"

DOI: 10.3389/fgene.2023.1028044

Abstract: Aims: Cuproptosis is a novel cell death pathway, and the regulatory mechanism in head and neck squamous cell carcinoma (HNSC) remains to be explored. We determined whether cuproptosis-related lncRNAs (CRLs) could predict prognosis in HNSC.… read more here.

Keywords: prognosis; related lncrnas; risk; hnsc ... See more keywords
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Acircadian rhythm-related gene signature for predicting survival and drug response in HNSC

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.1029676

Abstract: Head and neck squamous cell carcinoma (HNSC) represents one of the most common malignant carcinomas worldwide. Because the 5-year survival rate of patients with HNSC is poor, it is necessary to develop an effective signature… read more here.

Keywords: signature predicting; signature; hnsc; rhythm related ... See more keywords
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Identification of a Novel Cuproptosis-Related Gene Signature for Prognostic Implication in Head and Neck Squamous Carcinomas

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Published in 2022 at "Cancers"

DOI: 10.3390/cancers14163986

Abstract: Simple Summary Head and neck squamous carcinoma (HNSC) is a common malignancy that requires novel therapeutic targets. Cuproptosis is an emerging research hotspot. The purpose of this study is to mine the cuproptosis-related genes to… read more here.

Keywords: cuproptosis; gene signature; cuproptosis related; hnsc ... See more keywords
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Profilin 2 Promotes Proliferation and Metastasis of Head and Neck Cancer Cells by Regulating PI3K/AKT/β-Catenin Signaling Pathway

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Published in 2019 at "Oncology Research"

DOI: 10.3727/096504019x15579146061957

Abstract: Profilin 2 (PFN2) was found to be mainly expressed in neurons and involved in the development of the brain. In recent years, emerging evidence indicated that PFN2 is also significantly upregulated in various cancers including… read more here.

Keywords: catenin; pfn2; neck cancer; hnsc ... See more keywords
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Sterol regulatory element binding transcription factor 1 promotes proliferation and migration in head and neck squamous cell carcinoma

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Published in 2023 at "PeerJ"

DOI: 10.7717/peerj.15203

Abstract: Background Sterol-regulatory element-binding protein 1 (SREBP1) is a transcription factor involved in lipid metabolism that is encoded by sterol regulatory element binding transcription factor 1(SREBF1). SREBP1 overexpression is associated with the progression of several human… read more here.

Keywords: cell; proliferation migration; hnsc; srebf1 ... See more keywords