Articles with "hnscc patients" as a keyword



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Human Papillomavirus in Head and Neck Squamous Cell Carcinoma

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Published in 2017 at "Indian Journal of Surgery"

DOI: 10.1007/s12262-016-1585-8

Abstract: Head and neck squamous cell carcinomas (HNSCCs) are the most common cancers in India. Association, clinical presentations, and pathology of human papillomavirus (HPV) infection in 50 HNSCC patients were assessed and compared with 50 patients… read more here.

Keywords: hnscc; hpv; hpv positive; hnscc patients ... See more keywords
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Detection of Distant Metastases in Head and Neck Cancer: Changing Landscape

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Published in 2018 at "Advances in Therapy"

DOI: 10.1007/s12325-018-0662-8

Abstract: As head and neck squamous cell carcinoma (HNSCC) patients with distant metastases (DM) were generally treated only palliatively, the value of screening for DM was usually limited to attempts to avoid extensive locoregional treatment when… read more here.

Keywords: detection; fdg pet; distant metastases; hnscc patients ... See more keywords
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NRF2, p53, and p16: Predictive biomarkers to stratify human papillomavirus associated head and neck cancer patients for de-escalation of cancer therapy.

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Published in 2020 at "Critical reviews in oncology/hematology"

DOI: 10.1016/j.critrevonc.2020.102885

Abstract: Patients with HPV associated (HPV+ve) head and neck squamous cell carcinoma (HNSCC), particularly oropharyngeal cancer, show better treatment response, higher survival rates, and lower risks of recurrence as compared to HPV-ve HNSCC patients. Despite increased… read more here.

Keywords: cancer; hpv hnscc; hnscc patients; head neck ... See more keywords
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Plasma extracellular vesicle microRNA‐491‐5p as diagnostic and prognostic marker for head and neck squamous cell carcinoma

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Published in 2021 at "Cancer Science"

DOI: 10.1111/cas.15067

Abstract: Poor survival of patients with locally advanced head and neck squamous cell carcinoma (LA‐HNSCC) is partly due to early diagnosis difficulties and the lack of reliable biomarkers for predicting treatment outcomes. In the discovery cohort,… read more here.

Keywords: neck squamous; mir 491; hnscc; marker ... See more keywords
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536 Divergent cancer etiologies drive distinct B cell signatures and tertiary lymphoid structures in head and neck cancer

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Published in 2020 at "Journal for ImmunoTherapy of Cancer"

DOI: 10.1136/jitc-2020-sitc2020.0536

Abstract: Background Current FDA-approved immunotherapies aim to reinvigorate CD8+ T cells, but the contribution of the humoral arm of the immune response in human cancer remains poorly understood. B cells within tissues can mediate anti-tumor immunity… read more here.

Keywords: hpv hnscc; hnscc patients; cancer; cell ... See more keywords
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Identification of Immune-Related Prognostic Biomarkers Associated with HPV-Positive Head and Neck Squamous Cell Carcinoma

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Published in 2021 at "Journal of Immunology Research"

DOI: 10.1155/2021/6661625

Abstract: Background As a type of malignant tumor, head and neck squamous cell carcinoma (HNSCC) seriously threatens human health. This study is aimed at constructing a new, reliable prognostic model. Method The gene expression profile data… read more here.

Keywords: risk; cell; prognosis; hnscc ... See more keywords
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Abstract 2600: Resistance biomarkers in patients with head and neck squamous cell carcinoma treated with cetuximab

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Published in 2018 at "Cancer Research"

DOI: 10.1158/1538-7445.am2018-2600

Abstract: BACKGROUND: Cetuximab, a monoclonal antibody targeting EGFR, improves overall survival in the locally advanced setting in combination with radiotherapy and in first-line recurrent setting in combination with chemotherapy in HNSCC patients. No predictive biomarker of… read more here.

Keywords: patients treated; treated cetuximab; resistance; hnscc patients ... See more keywords
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Salivary microRNA miR-let-7a-5p and miR-3928 could be used as potential diagnostic bio-markers for head and neck squamous cell carcinoma

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Published in 2020 at "PLoS ONE"

DOI: 10.1371/journal.pone.0221779

Abstract: Backgrounds MicroRNAs (miRNA) are a class of non-protein-coding RNAs that have significant biological and pathological functions. The importance of miRNAs as potential cancer diagnostic biomarkers is gaining attention due to their influence in the regulation… read more here.

Keywords: mir 3928; mir let; healthy controls; mir ... See more keywords
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The overexpression of salivary cytokeratins as potential diagnostic biomarkers in head and neck squamous cell carcinomas

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Published in 2017 at "Oncotarget"

DOI: 10.18632/oncotarget.19731

Abstract: Background Cytokeratin (CK) intermediate filaments are demonstrated to have enormous potential in regulating cellular motility and cancer progression. There are more than 20 divergent CKs that have been identified, of which CK 8, 17, 18… read more here.

Keywords: healthy controls; squamous cell; hnscc; hnscc patients ... See more keywords
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Identification and validation of neurotrophic factor-related genes signature in HNSCC to predict survival and immune landscapes

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Published in 2022 at "Frontiers in Genetics"

DOI: 10.3389/fgene.2022.1010044

Abstract: Background: Head and neck squamous cell carcinoma (HNSCC) is the seventh most common type of cancer worldwide. Its highly aggressive and heterogeneous nature and complex tumor microenvironment result in variable prognosis and immunotherapeutic outcomes for… read more here.

Keywords: hnscc patients; prognosis; risk; hnscc ... See more keywords
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Survival association of XRCC1 for patients with head and neck squamous cell carcinoma: A systematic review and meta-analysis

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Published in 2023 at "Frontiers in Genetics"

DOI: 10.3389/fgene.2022.1035910

Abstract: Background: Epidemiologic studies have demonstrated that X-ray repair cross-complementary group 1 (XRCC1) is one of the susceptibility factors in head and neck squamous cell carcinoma (HNSCC) patients. However, its clinical prognostic impact remains controversial. Thus,… read more here.

Keywords: xrcc1; survival; hnscc patients; meta analysis ... See more keywords