Abstract B032: Proteomic analysis reveals alterations in apoptotic signaling machinery in HPV-associated cancers and identifies BRD4 and BCL2 as potential therapeutic targets in HPV-positive HNSCCs
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DOI: 10.1158/1535-7163.targ-19-b032
Abstract: Human papillomaviruses (HPV) are among the most common viral causes of cancer; infections account for a majority of cervical squamous cell carcinomas and endocervical adenocarcinomas (CESCs) and oropharyngeal squamous cell carcinomas. HPV-positive cancers demonstrate well-established… read more here.
Keywords: hpv positive; cancer; cescs; hpv ... See more keywords
Human Mesenchymal Stromal Cells Do Not Cause Radioprotection of Head-and-Neck Squamous Cell Carcinoma
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DOI: 10.3390/ijms23147689
Abstract: Radiotherapy of head-and-neck squamous cell carcinoma (HNSCC) can cause considerable normal tissue injuries, and mesenchymal stromal cells (MSCs) have been shown to aid regeneration of irradiation-damaged normal tissues. However, utilization of MSC-based treatments for HNSCC… read more here.
Keywords: cell; head neck; squamous cell; neck squamous ... See more keywords
Combination RSL3 Treatment Sensitizes Ferroptosis- and EGFR-Inhibition-Resistant HNSCCs to Cetuximab
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DOI: 10.3390/ijms23169014
Abstract: Head and neck squamous cell carcinomas (HNSCCs) are a type of cancer originating in the mucosal epithelium of the mouth, pharynx, and larynx, the sixth most common cancer in the world. However, there is no… read more here.
Keywords: cell; carcinoma cells; egfr inhibition; treatment ... See more keywords