A FRET-based biosensor for targeting the hNTH1-YB1 interface as a potential anti-cancer drug target.
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DOI: 10.1021/acschembio.9b01023
Abstract: The Y-box binding protein 1 (YB1) is an established metastatic marker: high expression and nuclear localization of YB1 correlate with tumor aggressiveness, drug resistance and poor patient survival in various tumors. In the nucleus, YB1… read more here.
Keywords: drug; based biosensor; fret based; hnth1 yb1 ... See more keywords