Articles with "hoc analysis" as a keyword



Patterns of Antifungal Resistance in Adult Patients With Fungal Keratitis in South India: A Post Hoc Analysis of 3 Randomized Clinical Trials.

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Published in 2022 at "JAMA ophthalmology"

DOI: 10.1001/jamaophthalmol.2021.5765

Abstract: Importance Antifungal resistance has been shown to impact treatment success, but research analyzing antifungal resistance is scarce. Objective To evaluate changes in antifungal resistance over time. Design, Setting, and Participants Ad hoc analysis of 3… read more here.

Keywords: hoc analysis; antifungal resistance; fold increase; resistance ... See more keywords

Twenty‐year survival outcomes after multipeptide vaccination for resected high‐risk melanoma: A post‐hoc analysis of a randomized clinical trial

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Published in 2025 at "International Journal of Cancer"

DOI: 10.1002/ijc.70006

Abstract: In this post‐hoc analysis, we report long‐term clinical outcomes of a randomized phase II clinical trial (Mel39, NCT00938223) that tested the immunogenicity of two multipeptide vaccines designed to stimulate CD8+ T cells in patients with… read more here.

Keywords: hoc analysis; clinical trial; response; melanoma ... See more keywords
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Dose-dependent effects of insoluble fibre on glucose metabolism: a stratified post hoc analysis of the Optimal Fibre Trial (OptiFiT)

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Published in 2021 at "Acta Diabetologica"

DOI: 10.1007/s00592-021-01772-0

Abstract: As the first long-term RCT on insoluble cereal fibre, the optimal fibre trial demonstrated glycometabolic benefits, confirming cohort studies. The combined study intervention of lifestyle recommendations and supplementation with insoluble oat hulls fibre allows to… read more here.

Keywords: hoc analysis; post hoc; fibre trial; optimal fibre ... See more keywords

Role of clipping in aneurysmal subarachnoid hemorrhage: a post hoc analysis of the Earlydrain trial

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Published in 2024 at "Neurosurgical Review"

DOI: 10.1007/s10143-024-03057-w

Abstract: The choice between clipping and coiling of ruptured cerebral aneurysms in subarachnoid hemorrhage (SAH) remains controversial. The recently published Earlydrain trial provides the opportunity to analyze the latest clip-to-coil ratio in German-speaking countries and to… read more here.

Keywords: hoc analysis; analysis; trial; earlydrain trial ... See more keywords

Evinacumab Reduces Triglyceride-Rich Lipoproteins in Patients with Hyperlipidemia: A Post-Hoc Analysis of Three Randomized Clinical Trials

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Published in 2024 at "Cardiovascular Drugs and Therapy"

DOI: 10.1007/s10557-024-07567-z

Abstract: Natural selection (Mendelian randomization) studies support a causal relationship between elevated triglyceride-rich lipoproteins (TRLs) and atherosclerotic cardiovascular disease (ASCVD). This post-hoc analysis assessed the efficacy of evinacumab in reducing TRLs in patient cohorts from three… read more here.

Keywords: triglyceride rich; hoc analysis; trial; rich lipoproteins ... See more keywords

Guided de-escalation of DAPT in acute coronary syndrome patients undergoing percutaneous coronary intervention with BVS implantation: a post-hoc analysis from the randomized TROPICAL-ACS trial

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Published in 2019 at "Journal of Thrombosis and Thrombolysis"

DOI: 10.1007/s11239-019-01811-2

Abstract: To investigate the safety and efficacy of an early platelet function testing (PFT)-guided de-escalation of dual antiplatelet treatment (DAPT) in acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI) with bioresorbable vascular scaffolds (BVS).… read more here.

Keywords: hoc analysis; post hoc; acs; implantation ... See more keywords

Smoking Is Correlated to Internal Hernia After Gastric Bypass Surgery: a Post hoc Analysis of Data from a Randomized Clinical Trial

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Published in 2024 at "Obesity Surgery"

DOI: 10.1007/s11695-024-07097-5

Abstract: Internal herniation is a well-known complication of laparoscopic Roux-en-Y gastric bypass (L-RYGB). The aim of this study was to evaluate smoking as an independent risk factor for internal herniation after L-RYGB. This study was performed… read more here.

Keywords: hoc analysis; risk; herniation; smoking ... See more keywords

Improvements in Plaque Psoriasis Associated with Calcipotriol/Betamethasone Aerosol Foam Treatment: A Post Hoc Analysis of Non-interventional Studies and Clinical Experience

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Published in 2024 at "Dermatology and Therapy"

DOI: 10.1007/s13555-024-01108-0

Abstract: Plaque psoriasis is a chronic relapsing inflammatory skin disease that is associated with extensive disease burden that often requires long-term therapy. Treatment of psoriasis with 4 weeks of the aerosol foam formulation of calcipotriol/betamethasone dipropionate… read more here.

Keywords: treatment; hoc analysis; cal foam; psoriasis ... See more keywords

Assessing Early Efficacy After Initiation of Once-Nightly Sodium Oxybate (ON-SXB; FT218) in Participants with Narcolepsy Type 1 or 2: A Post Hoc Analysis from the Phase 3 REST-ON Trial

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Published in 2025 at "CNS Drugs"

DOI: 10.1007/s40263-024-01143-7

Abstract: Once-nightly sodium oxybate (LUMRYZ™; ON-SXB; FT218) significantly improved narcolepsy symptoms in the phase 3 REST-ON trial. The objective of this post hoc analysis was to investigate the early efficacy of ON-SXB at weeks 1 (4.5-g… read more here.

Keywords: hoc analysis; sleep quality; efficacy; sxb ... See more keywords

Efficacy of adjunctive brexpiprazole on the core symptoms of major depressive disorder: A post hoc analysis of two pooled clinical studies.

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Published in 2018 at "Journal of affective disorders"

DOI: 10.1016/j.jad.2017.09.054

Abstract: BACKGROUND Patients with major depressive disorder (MDD) who do not adequately respond to antidepressant treatment (ADT) may benefit from adjunctive atypical antipsychotics; however, certain agents target specific symptoms of depression and not the full syndrome.… read more here.

Keywords: adjunctive brexpiprazole; post hoc; hoc analysis; core symptoms ... See more keywords

ALIROCUMAB REDUCES MAJOR CARDIOVASCULAR EVENTS IN INDIVIDUALS WITH ATHEROSCLEROTIC CARDIOVASCULAR DISEASE: A POST-HOC ANALYSIS OF ODYSSEY LONG TERM

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Published in 2017 at "Journal of the American College of Cardiology"

DOI: 10.1016/s0735-1097(17)33540-4

Abstract: Background: Individuals with elevated low density lipoprotein cholesterol (LDL-C) and atherosclerotic cardiovascular disease (ASCVD) are at increased risk for recurrent events. We present a post-hoc analysis of the efficacy and safety of alirocumab (ALI) vs.… read more here.

Keywords: post hoc; cardiovascular disease; hoc analysis; atherosclerotic cardiovascular ... See more keywords