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Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232415866
Abstract: Cisplatin (CDDP) is an efficient chemotherapeutic drug, whose use is associated with the development of serious undesired toxicities, such as nephrotoxicity. The human organic cation transporter 2 (hOCT2), which is highly expressed in the basolateral…
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Keywords:
development;
toxicity;
cddp;
hoct2 ... See more keywords
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Published in 2017 at "ADMET and DMPK"
DOI: 10.5599/admet.5.2.389
Abstract: The aim of this study was to assess the suitability of amiloride, rhodamine 6G and rhodamine 123 as non-radioactive substrates for characterizing hOCT2 using CHO cells. The uptake characteristics of these compounds were compared in…
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Keywords:
cells stably;
cho cells;
hoct2;
stably expressing ... See more keywords