Articles with "hoct2" as a keyword



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Exacerbation of Cisplatin Cellular Toxicity by Regulation of the Human Organic Cation Transporter 2 through Angiotensin II

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms232415866

Abstract: Cisplatin (CDDP) is an efficient chemotherapeutic drug, whose use is associated with the development of serious undesired toxicities, such as nephrotoxicity. The human organic cation transporter 2 (hOCT2), which is highly expressed in the basolateral… read more here.

Keywords: development; toxicity; cddp; hoct2 ... See more keywords
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Fluorescent organic cations for human OCT2 transporters screening: uptake in CHO cells stably expressing hOCT2

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Published in 2017 at "ADMET and DMPK"

DOI: 10.5599/admet.5.2.389

Abstract: The aim of this study was to assess the suitability of amiloride, rhodamine 6G and rhodamine 123 as non-radioactive substrates for characterizing hOCT2 using CHO cells. The uptake characteristics of these compounds were compared in… read more here.

Keywords: cells stably; cho cells; hoct2; stably expressing ... See more keywords