Holothuria leucospilota polysaccharides alleviate liver injury via AMPK and NF-κB signaling pathways in type 2 diabetic rats
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2021.104657
Abstract: Abstract The study evaluated the beneficial effects of orally administered Holothuria leucospilota polysaccharides (HLP) on liver injury in diabetic rats. The results showed that HLP regulated liver glycogen, glycosylated serum protein, aspartate aminotransferase (AST) and… read more here.
Keywords: holothuria leucospilota; polysaccharides alleviate; leucospilota polysaccharides; diabetic rats ... See more keywords
The Holothuria leucospilota genome elucidates sacrificial organ expulsion and bioadhesive trap enriched with amyloid-patterned proteins.
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2213512120
Abstract: Some tropical sea cucumbers of the family Holothuriidae can efficiently repel or even fatally ensnare predators by sacrificially ejecting a bioadhesive matrix termed the Cuvierian organ (CO), so named by the French zoologist Georges Cuvier… read more here.
Keywords: elucidates sacrificial; genome; holothuria leucospilota; leucospilota genome ... See more keywords
Extraction and Characterization of Organ Components of the Malaysian Sea Cucumber Holothuria leucospilota Yielded Bioactives Exhibiting Diverse Properties
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DOI: 10.1155/2019/2640684
Abstract: The aim of the present study was to extract and characterize bioactive components from separate body organs of Holothuria leucospilota. Preliminary qualitative assessment of the crude extracts was positive for phenols, terpenoids, carbohydrates, flavonoids, saponins,… read more here.
Keywords: methyl; characterization organ; sea; holothuria leucospilota ... See more keywords
Polysaccharides from Holothuria leucospilota Relieve Loperamide-Induced Constipation Symptoms in Mice
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DOI: 10.3390/ijms24032553
Abstract: A vital bioactive component of marine resources is Holothuria leucospilota polysaccharides (HLP). This study examined whether HLP could regulate intestinal flora to treat loperamide-induced constipation. Constipated mice showed signs of prolonged defecation (up by 60.79… read more here.
Keywords: loperamide induced; induced constipation; holothuria leucospilota; constipation symptoms ... See more keywords