Separation, purification, structures and anticoagulant activities of fucosylated chondroitin sulfates from Holothuria scabra.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2017.11.058
Abstract: In this study, a new fucosylated chondroitin sulfate (HsG) with an average molecular weight of 69.1 kDa was isolated from sea cucumber Holothuria scabra. We investigated the structure of the HsG by adopting monosaccharide composition analysis,… read more here.
Keywords: anticoagulant activities; fucosylated chondroitin; residues linked; fucopyranosyl ... See more keywords
Epidemiology of a SKin Ulceration Disease (SKUD) in the sea cucumber Holothuria scabra with a review on the SKUDs in Holothuroidea (Echinodermata)
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DOI: 10.1038/s41598-020-78876-0
Abstract: Aquacultivated sea cucumbers often suffer from SKin Ulceration Diseases (SKUDs). SKUDs have been observed in six holothuroid species from nine countries. All SKUDs present a similar symptom—the skin ulceration—and can be induced by bacteria, viruses,… read more here.
Keywords: sea; disease; skin ulceration; epidemiology ... See more keywords
Microwave-Assisted Desulfation of the Hemolytic Saponins Extracted from Holothuria scabra Viscera
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DOI: 10.3390/molecules27020537
Abstract: Saponins are plant and marine animal specific metabolites that are commonly considered as molecular vectors for chemical defenses against unicellular and pluricellular organisms. Their toxicity is attributed to their membranolytic properties. Modifying the molecular structures… read more here.
Keywords: viscera; desulfation hemolytic; microwave assisted; assisted desulfation ... See more keywords
2-Butoxytetrahydrofuran and Palmitic Acid from Holothuria scabra Enhance C. elegans Lifespan and Healthspan via DAF-16/FOXO and SKN-1/NRF2 Signaling Pathways
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15111374
Abstract: Extracts from a sea cucumber, Holothuria scabra, have been shown to exhibit various pharmacological properties including anti-oxidation, anti-aging, anti-cancer, and anti-neurodegeneration. Furthermore, certain purified compounds from H. scabra displayed neuroprotective effects against Parkinson’s and Alzheimer’s… read more here.
Keywords: holothuria scabra; skn; acid; palmitic acid ... See more keywords