Separation, purification, structures and anticoagulant activities of fucosylated chondroitin sulfates from Holothuria scabra.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2017.11.058
Abstract: In this study, a new fucosylated chondroitin sulfate (HsG) with an average molecular weight of 69.1 kDa was isolated from sea cucumber Holothuria scabra. We investigated the structure of the HsG by adopting monosaccharide composition analysis,… read more here.
Keywords: anticoagulant activities; fucosylated chondroitin; residues linked; fucopyranosyl ... See more keywords
Chromosomal-level genome assembly and annotation of the tropical sea cucumber Holothuria scabra
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Data"
DOI: 10.1038/s41597-024-03340-x
Abstract: Holothuria scabra, a commercially valuable yet ecologically vulnerable tropical holothuroid, has experienced a severe decline in its wild populations, especially in China. Genomic resources are crucial for the development of effective genomic breeding projects and… read more here.
Keywords: holothuria scabra; level; chromosome level; genome ... See more keywords
Epidemiology of a SKin Ulceration Disease (SKUD) in the sea cucumber Holothuria scabra with a review on the SKUDs in Holothuroidea (Echinodermata)
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-78876-0
Abstract: Aquacultivated sea cucumbers often suffer from SKin Ulceration Diseases (SKUDs). SKUDs have been observed in six holothuroid species from nine countries. All SKUDs present a similar symptom—the skin ulceration—and can be induced by bacteria, viruses,… read more here.
Keywords: sea; disease; skin ulceration; epidemiology ... See more keywords
The neuropeptidomes of the sea cucumbers Stichopus cf. horrens and Holothuria scabra
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-85696-7
Abstract: The Philippines is a renowned marine biodiversity hotspot, home to several sea cucumber species with unusual biological traits. Among these, Stichopus cf. horrens is notable for its ability to undergo rapid body wall liquefaction when… read more here.
Keywords: holothuria scabra; neuropeptidomes sea; sea cucumbers; neurobiology ... See more keywords
Diversity and characterization of culturable fungi associated with the marine sea cucumber Holothuria scabra
Sign Up to like & getrecommendations! Published in 2024 at "PLOS ONE"
DOI: 10.1371/journal.pone.0296499
Abstract: Fungi associated with the marine echinoderm, Holothuria scabra, produces extracellular enzymes and bioactive metabolites, and mycoviruses that could be used for biotechnological and pharmaceutical applications. The species identification based on molecular and morphological characteristics classified… read more here.
Keywords: holothuria scabra; culturable fungi; fungi associated; diversity ... See more keywords
Before It Is Too Late: Current Genetic Diversity Status of the Exploited Sandfish Holothuria Scabra (Echinodermata: Holothuroidea)
Sign Up to like & getrecommendations! Published in 2024 at "Sains Malaysiana"
DOI: 10.17576/jsm-2024-5307-02
Abstract: The sandfish Holothuria scabra is a well exploited and among the highest-valued sea cucumber species. Owing to its economic importance and the global expansion of sea cucumber fisheries that could lead to overfishing, the aquaculture… read more here.
Keywords: holothuria scabra; sandfish holothuria; genetic diversity; sea ... See more keywords
DETERMINATION OF PROTEIN TRANSPORTERS FOR THE ABSORPTION OF ZN-PEPTIDES FROM HOLOTHURIA SCABRA THROUGH NETWORK PHARMACOLOGY WITH MOLECULAR SIMULATION APPROACH
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of Applied Pharmaceutics"
DOI: 10.22159/ijap.2025v17i6.55054
Abstract: Objective: This study aimed to identify key genes and proteins involved in zinc homeostasis and to evaluate the potential of sea cucumber (Holothuria scabra) peptides as zinc-binding agents targeting the zinc transporter protein ZIP2, which… read more here.
Keywords: protein; zinc homeostasis; pharmacology; holothuria scabra ... See more keywords
Microwave-Assisted Desulfation of the Hemolytic Saponins Extracted from Holothuria scabra Viscera
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27020537
Abstract: Saponins are plant and marine animal specific metabolites that are commonly considered as molecular vectors for chemical defenses against unicellular and pluricellular organisms. Their toxicity is attributed to their membranolytic properties. Modifying the molecular structures… read more here.
Keywords: viscera; desulfation hemolytic; microwave assisted; assisted desulfation ... See more keywords
2-Butoxytetrahydrofuran and Palmitic Acid from Holothuria scabra Enhance C. elegans Lifespan and Healthspan via DAF-16/FOXO and SKN-1/NRF2 Signaling Pathways
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15111374
Abstract: Extracts from a sea cucumber, Holothuria scabra, have been shown to exhibit various pharmacological properties including anti-oxidation, anti-aging, anti-cancer, and anti-neurodegeneration. Furthermore, certain purified compounds from H. scabra displayed neuroprotective effects against Parkinson’s and Alzheimer’s… read more here.
Keywords: holothuria scabra; skn; acid; palmitic acid ... See more keywords