More than just a hole in the heart: a case of Holt-Oram syndrome with severe left ventricular dysfunction
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American College of Cardiology"
DOI: 10.1016/s0735-1097(18)33040-7
Abstract: Atrial septal defects (ASDs) are commonly encountered and can be associated with extra-cardiac conditions. Holt-Oram, although rare, is such an example. A 35-year-old healthy man was admitted with 1 month of progressive dyspnea, chest tightness… read more here.
Keywords: heart case; hole heart; holt oram; case holt ... See more keywords
Congenital extremity anomalies with a TBX5 pathogenic variant in consecutive IVF assisted pregnancies: a case report of Holt-Oram Syndrome
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Obstetrics and Gynaecology"
DOI: 10.1080/01443615.2021.1916895
Abstract: A 37-year-old, G3P0, with a pregnancy that arose after in vitro fertilisation, attended for nuchal translucency sonogram at 13weeks and 3 days of gestation. This scan was notable for fixed deviation and four visualised digits… read more here.
Keywords: holt oram; gestation; pregnancy; pathogenic variant ... See more keywords
Holt–Oram Syndrome Associated with Complex Congenital Heart Disease: A Rare Case Presentation and Literature Review
Sign Up to like & getrecommendations! Published in 2020 at "Open Access Macedonian Journal of Medical Sciences"
DOI: 10.3889/oamjms.2020.4287
Abstract: BACKGROUND: First described by Holt and Oram in 1960 in a four-generation family with atrial septal defects and thumb abnormalities, is an inherited disorder characterized by abnormalities of the upper limbs and heart. This syndrome… read more here.
Keywords: associated complex; heart; holt oram; case ... See more keywords
Holt–Oram Syndrome: Anesthetic Challenges and Safe Outcome
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DOI: 10.4103/0971-9784.197849
Abstract: Holt-Oram syndrome (HOS) is an autosomal dominant disease with skeletal and cardiac manifestations. We here are presenting a 31-year-old man and a diagnosed case of HOS, with an ulceroproliferative lesion on lateral border of the… read more here.
Keywords: anesthetic challenges; holt oram; syndrome anesthetic; challenges safe ... See more keywords
Steroid-associated bradycardia in a newly diagnosed B precursor acute lymphoblastic leukemia patient with Holt–Oram syndrome
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Pediatric Cardiology"
DOI: 10.4103/apc.apc_87_19
Abstract: Holt–Oram syndrome (HOS) (OMIM#142900) is a rare condition with upper extremity malformations as well as structural and conduction cardiac anomalies. There are sparse reports in the literature documenting malignancy in association with HOS. We report… read more here.
Keywords: precursor acute; holt oram; lymphoblastic leukemia; acute lymphoblastic ... See more keywords