T cells engineered to home in on brain cancer
Sign Up to like & getrecommendations! Published in 2018 at "Nature"
DOI: 10.1038/d41586-018-05883-7
Abstract: Immunotherapies activate T cells to destroy tumours, but the approach has failed in some brain cancers. A strategy to improve migration of T cells across the blood–brain barrier could overcome this limitation.A synthetic ligand enhances… read more here.
Keywords: brain cancer; cells engineered; engineered home; home brain ... See more keywords
T cells home in on brain cancer
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Immunology"
DOI: 10.1038/s41577-018-0069-4
Abstract: T cells are engineered to home specifically to brain tumours. read more here.
Keywords: brain cancer; home; home brain; cells home ... See more keywords
Modified T Cells Home to Brain Tumors.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-nb2018-125
Abstract: In a recent study, researchers investigated why brain cancers are impervious to T cells, and used their findings to create reengineered T cells that are better able to move into tumors. Their "homing system" could… read more here.
Keywords: modified cells; home brain; cells home; brain ... See more keywords