Home-cage anxiety levels in a transgenic rat model for Spinocerebellar ataxia type 17 measured by an approach-avoidance task: The light spot test
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Neuroscience Methods"
DOI: 10.1016/j.jneumeth.2017.08.012
Abstract: BACKGROUND Measuring anxiety in a reliable manner is essential for behavioural phenotyping of rodent models such as the rat model for Spinocerebellar ataxia type 17 (SCA17) where anxiety is reported in patients. An automated tool… read more here.
Keywords: anxiety; rat model; home cage; test ... See more keywords
Coding of “Home Cage” by PFC Neurons
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2018.09.042
Abstract: Contexts play critical roles in many important aspects of an animal's routine functions, such as the interpretation of incoming signals and retrieved memories. The roles played by prefrontal cortex (PFC) neurons in the coding of… read more here.
Keywords: home cage; home; pfc neurons; neurons coding ... See more keywords
Development of behavioral patterns in young C57BL/6J mice: a home cage-based study
Sign Up to like & getrecommendations! Published in 2022 at "Scientific Reports"
DOI: 10.1038/s41598-022-06395-1
Abstract: Evidence exists that behavioral patterns only stabilize once mice reach adulthood. Detailed information about the course of behavioral patterns is of particular relevance for neuroscientific research and for the assessment of cumulative severity in genetically… read more here.
Keywords: development; age; behavioral patterns; mice ... See more keywords
The Value of Homework: Exposure to Odors in the Home Cage Enhances Odor-Discrimination Learning in Mice
Sign Up to like & getrecommendations! Published in 2019 at "Chemical Senses"
DOI: 10.1093/chemse/bjy083
Abstract: Perceptual learning is an enhancement in discriminability of similar stimuli following experience with those stimuli. Here, we examined the efficacy of adding additional active training following a standard training session, compared with additional stimulus exposure… read more here.
Keywords: home cage; odor discrimination; exposure;
Non-invasive detection of narcolepsy type I phenotypical features and disease progression by continuous home-cage monitoring of activity in two mouse models: the HCRT-KO and DTA model.
Sign Up to like & getrecommendations! Published in 2023 at "Sleep"
DOI: 10.1093/sleep/zsad144
Abstract: Narcolepsy type 1 (NT1) is a neurological disorder caused by disruption of hypocretin (HCRT; or orexin) neurotransmission leading to fragmented sleep/wake states, excessive daytime sleepiness (EDS), and cataplexy (abrupt muscle atonia during wakefulness). Electroencephalography and… read more here.
Keywords: home cage; phenotypical features; activity; model ... See more keywords
Neph2/Kirrel3 regulates sensory input, motor coordination, and home‐cage activity in rodents
Sign Up to like & getrecommendations! Published in 2018 at "Genes"
DOI: 10.1111/gbb.12516
Abstract: Adhesion molecules of the immunoglobulin superfamily (IgSF) are essential for neuronal synapse development across evolution and control various aspects of synapse formation and maturation. Neph2, also known as Kirrel3, is an IgSF adhesion molecule implicated… read more here.
Keywords: home cage; motor; synapse formation; neph2 kirrel3 ... See more keywords
Home, head direction stability, and grid cell distortion
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neurophysiology"
DOI: 10.1152/jn.00518.2019
Abstract: The home is a unique location in the life of humans and animals. In rats, home presents itself as a multicompartmental space that involves integrating navigation through subspaces. Here we embedded the laboratory rat’s home… read more here.
Keywords: home cage; home; head direction;
An Automated Home-Cage System to Assess Learning and Performance of a Skilled Motor Task in a Mouse Model of Huntington’s Disease
Sign Up to like & getrecommendations! Published in 2017 at "eNeuro"
DOI: 10.1523/eneuro.0141-17.2017
Abstract: Visual Abstract Behavioral testing is a critical step in assessing the validity of rodent models of neurodegenerative disease, as well as evaluating the efficacy of pharmacological interventions. In models of Huntington’s disease (HD), a gradual… read more here.
Keywords: home cage; task; motor; mouse ... See more keywords
LIQ HD (Lick Instance Quantifier Home Cage Device): An Open-Source Tool for Recording Undisturbed Two-Bottle Drinking Behavior in a Home Cage Environment
Sign Up to like & getrecommendations! Published in 2022 at "eNeuro"
DOI: 10.1523/eneuro.0506-22.2023
Abstract: Abstract Investigation of rodent drinking behavior has provided insight into drivers of thirst, circadian rhythms, anhedonia, and drug and ethanol consumption. Traditional methods of recording fluid intake involve weighing bottles, which is cumbersome and lacks… read more here.
Keywords: home; open source; two bottle; home cage ... See more keywords
Exhaustive Multi-Parametric Assessment of the Behavioral Array of Daily Activities of Mice Using Cluster and Factor Analysis
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Behavioral Neuroscience"
DOI: 10.3389/fnbeh.2018.00187
Abstract: Using automated supervised behavioral assessment software, we recorded and analyzed 24 h non-interrupted recordings of mice for a duration of 11 days. With the assistance of free R programming, we used correlation matrix-based hierarchical clustering… read more here.
Keywords: home cage; factor analysis;
Measuring Locomotor Activity and Behavioral Aspects of Rodents Living in the Home-Cage
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Behavioral Neuroscience"
DOI: 10.3389/fnbeh.2022.877323
Abstract: Automatization and technological advances have led to a larger number of methods and systems to monitor and measure locomotor activity and more specific behavior of a wide variety of animal species in various environmental conditions… read more here.
Keywords: locomotor activity; behavioral aspects; home cage; locomotor ... See more keywords