Articles with "homeobox" as a keyword



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The distribution of some homeobox proteins in the bovine placenta during gestation.

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Published in 2021 at "Theriogenology"

DOI: 10.1016/j.theriogenology.2021.02.015

Abstract: Homeobox proteins are transcription factors known to be involved in the molecular basics of body model formation and transformation. Some homeobox proteins are known to play critical roles in the control of the extraembryonic development… read more here.

Keywords: distribution homeobox; homeobox proteins; placenta gestation; homeobox ... See more keywords
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PRD-Class Homeobox Genes in Bovine Early Embryos: Function, Evolution, and Overlapping Roles

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Published in 2022 at "Molecular Biology and Evolution"

DOI: 10.1093/molbev/msac098

Abstract: Abstract Eutherian Totipotent Cell Homeobox (ETCHbox) genes are mammalian-specific PRD-class homeobox genes with conserved expression in the preimplantation embryo but fast-evolving and highly divergent sequences. Here, we exploit an ectopic expression approach to examine the… read more here.

Keywords: homeobox genes; etchbox genes; class homeobox; homeobox ... See more keywords
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MEOX2 homeobox gene promotes growth of malignant gliomas.

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Published in 2022 at "Neuro-oncology"

DOI: 10.1093/neuonc/noac110

Abstract: BACKGROUND Glioblastoma (GBM) is an aggressive tumor that frequently exhibits gain of chromosome 7, loss of chromosome 10 and aberrantly activated receptor tyrosine kinase signaling pathways. Previously, we identified Mesenchyme Homeobox 2 (MEOX2), a gene… read more here.

Keywords: gbm; growth; homeobox; meox2 ... See more keywords
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Diversity, duplication, and genomic organization of homeobox genes in Lepidoptera

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Published in 2022 at "Genome Research"

DOI: 10.1101/gr.277118.122

Abstract: Homeobox genes encode transcription factors with essential roles in patterning and cell fate in developing animal embryos. Many homeobox genes, including Hox and NK genes, are arranged in gene clusters, a feature likely related to… read more here.

Keywords: homeobox; homeobox genes; cluster; lepidoptera ... See more keywords
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NKL homeobox gene activities in normal and malignant myeloid cells

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Published in 2019 at "PLoS ONE"

DOI: 10.1371/journal.pone.0226212

Abstract: Recently, we have documented a hematopoietic NKL-code mapping physiological expression patterns of NKL homeobox genes in early hematopoiesis and in lymphopoiesis, which spotlights genes deregulated in lymphoid malignancies. Here, we enlarge this map to include… read more here.

Keywords: homeobox genes; homeobox; nkl homeobox; homeobox gene ... See more keywords
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NKL homeobox gene NKX2-2 is aberrantly expressed in Hodgkin lymphoma

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Published in 2018 at "Oncotarget"

DOI: 10.18632/oncotarget.26459

Abstract: NKL homeobox genes encode basic transcriptional regulators of cell and tissue differentiation. Recently, we described a hematopoietic NKL-code comprising nine specific NKL homeobox genes expressed in normal hematopoietic stem cells, lymphoid progenitors and during lymphopoiesis,… read more here.

Keywords: gene nkx2; nkl homeobox; hodgkin lymphoma; homeobox ... See more keywords
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Assessment of Expression of Homeobox A5 in Endometrial Cancer on the mRNA and Protein Level

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Published in 2019 at "Current Pharmaceutical Biotechnology"

DOI: 10.2174/1389201021666191227121627

Abstract: Background Endometrial cancer is one of the most common gynecological cancer in the developed countries and occurs mainly in postmenopausal women. Angiogenesis is important for cancer formation as it provides nutrients for growing tumor mass.… read more here.

Keywords: mrna protein; hoxa5; endometrial cancer; expression ... See more keywords
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ERN1 knockdown modifies the effect of glucose deprivation on homeobox gene expressions in U87 glioma cells

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Published in 2020 at "Endocrine Regulations"

DOI: 10.2478/enr-2020-0022

Abstract: Abstract Objective. The aim of the present investigation was to study the expression of genes encoding homeobox proteins ZEB2 (zinc finger E-box binding homeobox 2), TGIF1 (TGFB induced factor homeobox 1), SPAG4 (sperm associated antigen… read more here.

Keywords: glioma; glucose deprivation; glioma cells; homeobox ... See more keywords
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The involvement of homeobox-C 4 in predicting prognosis and unraveling immune landscape across multiple cancers via integrated analysis

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Published in 2022 at "Frontiers in Genetics"

DOI: 10.3389/fgene.2022.1021473

Abstract: Background: There has been growing evidence that the aberrantly expressed Homeobox-C 4 (HOXC4) plays crucial roles in the development of some cancer types. However, it remains unclear as far as its expression patterns and prognostic… read more here.

Keywords: prognosis; expression; analysis; homeobox ... See more keywords
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Genetic Regulation of Vertebrate Forebrain Development by Homeobox Genes

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Published in 2022 at "Frontiers in Neuroscience"

DOI: 10.3389/fnins.2022.843794

Abstract: Forebrain development in vertebrates is regulated by transcription factors encoded by homeobox, bHLH and forkhead gene families throughout the progressive and overlapping stages of neural induction and patterning, regional specification and generation of neurons and… read more here.

Keywords: transcription factors; development; forebrain development; homeobox ... See more keywords