The rax homeobox gene is mutated in the eyeless axolotl, Ambystoma mexicanum
Sign Up to like & getrecommendations! Published in 2020 at "Developmental Dynamics"
DOI: 10.1002/dvdy.246
Abstract: Vertebrate eye formation requires coordinated inductive interactions between different embryonic tissue layers, first described in amphibians. A network of transcription factors and signaling molecules controls these steps, with mutations causing severe ocular, neuronal, and craniofacial… read more here.
Keywords: eyeless axolotl; mutated eyeless; gene mutated; rax homeobox ... See more keywords
Agenesis of the putamen and globus pallidus caused by recessive mutations in the homeobox gene GSX2
Sign Up to like & getrecommendations! Published in 2019 at "Brain"
DOI: 10.1093/brain/awz247
Abstract: Congenital malformations of the basal ganglia are rare. De Mori et al. describe a novel syndrome of severe dystonic tetraparesis and intellectual impairment, with hypo/agenesis of the basal ganglia. The syndrome is caused by recessive… read more here.
Keywords: agenesis; recessive mutations; homeobox gene; caused recessive ... See more keywords
The role of insulin-like growth factor 2 receptor-mediated homeobox gene expression in human placental apoptosis, and its implications in idiopathic fetal growth restriction.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular human reproduction"
DOI: 10.1093/molehr/gaz047
Abstract: Fetal growth restriction (FGR) is caused by poor placental development and function early in gestation. It is well known that placentas from women with FGR exhibit reduced cell growth, elevated levels of apoptosis and perturbed… read more here.
Keywords: cell; apoptosis; expression; homeobox gene ... See more keywords
Of eyes and embryos: subfunctionalization of the CRX homeobox gene in mammalian evolution
Sign Up to like & getrecommendations! Published in 2019 at "Proceedings of the Royal Society B: Biological Sciences"
DOI: 10.1098/rspb.2019.0830
Abstract: ETCHbox genes are fast-evolving homeobox genes present only in eutherian (placental) mammals which originated by duplication and divergence from a conserved homeobox gene, Cone-rod homeobox (CRX). While expression and function of CRX are restricted to… read more here.
Keywords: subfunctionalization; crx; homeobox gene; etchbox genes ... See more keywords
NKL homeobox gene activities in normal and malignant myeloid cells
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DOI: 10.1371/journal.pone.0226212
Abstract: Recently, we have documented a hematopoietic NKL-code mapping physiological expression patterns of NKL homeobox genes in early hematopoiesis and in lymphopoiesis, which spotlights genes deregulated in lymphoid malignancies. Here, we enlarge this map to include… read more here.
Keywords: homeobox genes; homeobox; nkl homeobox; homeobox gene ... See more keywords
NKL homeobox gene NKX2-2 is aberrantly expressed in Hodgkin lymphoma
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DOI: 10.18632/oncotarget.26459
Abstract: NKL homeobox genes encode basic transcriptional regulators of cell and tissue differentiation. Recently, we described a hematopoietic NKL-code comprising nine specific NKL homeobox genes expressed in normal hematopoietic stem cells, lymphoid progenitors and during lymphopoiesis,… read more here.
Keywords: gene nkx2; nkl homeobox; hodgkin lymphoma; homeobox ... See more keywords
Genome-Wide Identification, Expansion, and Evolution Analysis of Homeobox Gene Family Reveals TALE Genes Important for Secondary Cell Wall Biosynthesis in Moso Bamboo (Phyllostachys edulis)
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23084112
Abstract: The TALE gene family is a subfamily of the homeobox gene family and has been implicated in regulating plant secondary growth. However, reports about the evolutionary history and function of the TALE gene family in… read more here.
Keywords: gene family; homeobox gene; moso bamboo; gene ... See more keywords