Architects meets Repairers: The interplay between homeobox genes and DNA repair.
Sign Up to like & getrecommendations! Published in 2019 at "DNA repair"
DOI: 10.1016/j.dnarep.2018.10.007
Abstract: Homeobox genes are widely considered the major protagonists of embryonic development and tissue formation. For the past decades, it was established that the deregulation of these genes is intimately related to developmental abnormalities and a… read more here.
Keywords: homeobox genes; genes dna; dna repair; interplay homeobox ... See more keywords
PRD-Class Homeobox Genes in Bovine Early Embryos: Function, Evolution, and Overlapping Roles
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Biology and Evolution"
DOI: 10.1093/molbev/msac098
Abstract: Abstract Eutherian Totipotent Cell Homeobox (ETCHbox) genes are mammalian-specific PRD-class homeobox genes with conserved expression in the preimplantation embryo but fast-evolving and highly divergent sequences. Here, we exploit an ectopic expression approach to examine the… read more here.
Keywords: homeobox genes; etchbox genes; class homeobox; homeobox ... See more keywords
Diversity, duplication, and genomic organization of homeobox genes in Lepidoptera
Sign Up to like & getrecommendations! Published in 2022 at "Genome Research"
DOI: 10.1101/gr.277118.122
Abstract: Homeobox genes encode transcription factors with essential roles in patterning and cell fate in developing animal embryos. Many homeobox genes, including Hox and NK genes, are arranged in gene clusters, a feature likely related to… read more here.
Keywords: homeobox; homeobox genes; cluster; lepidoptera ... See more keywords
Prepatterning of Papilio xuthus caterpillar camouflage is controlled by three homeobox genes: clawless, abdominal-A, and Abdominal-B
Sign Up to like & getrecommendations! Published in 2019 at "Science Advances"
DOI: 10.1126/sciadv.aav7569
Abstract: Three homeobox genes regulate prepatterning of caterpillar camouflage design in the swallowtail butterfly, Papilio xuthus. Color patterns often function as camouflage to protect insects from predators. In most swallowtail butterflies, younger larvae mimic bird droppings… read more here.
Keywords: papilio xuthus; homeobox genes; three homeobox; camouflage ... See more keywords
NKL homeobox gene activities in normal and malignant myeloid cells
Sign Up to like & getrecommendations! Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0226212
Abstract: Recently, we have documented a hematopoietic NKL-code mapping physiological expression patterns of NKL homeobox genes in early hematopoiesis and in lymphopoiesis, which spotlights genes deregulated in lymphoid malignancies. Here, we enlarge this map to include… read more here.
Keywords: homeobox genes; homeobox; nkl homeobox; homeobox gene ... See more keywords
Deregulated NKL Homeobox Genes in B-Cell Lymphoma
Sign Up to like & getrecommendations! Published in 2019 at "Cancers"
DOI: 10.3390/cancers11121874
Abstract: Recently, we have described physiological expression patterns of NKL homeobox genes in early hematopoiesis and in subsequent lymphopoiesis. We identified nine genes which constitute the so-called NKL-code. Aberrant overexpression of code-members or ectopically activated non-code… read more here.
Keywords: nkl homeobox; deregulated nkl; homeobox genes; genes cell ... See more keywords
NKL Homeobox Genes NKX2-3 and NKX2-4 Deregulate Megakaryocytic-Erythroid Cell Differentiation in AML
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms222111434
Abstract: NKL homeobox genes encode transcription factors that impact normal development and hematopoietic malignancies if deregulated. Recently, we established an NKL-code that describes the physiological expression pattern of eleven NKL homeobox genes in the course of… read more here.
Keywords: genes nkx2; nkl homeobox; homeobox genes; expression ... See more keywords