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   Articles with "homeostasis" as a keyword



Antipsychotic Drugs and Dysregulated Glucose Homeostasis: A Systematic Review and Meta-Analysis.

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recommendations! Published in 2025 at "JAMA psychiatry"

DOI: 10.1001/jamapsychiatry.2025.2240

Abstract: Importance Antipsychotic drug (AP)-induced glucose homeostasis changes are often attributed to AP-induced weight gain. Nevertheless, dysregulated glucose control can occur independently of weight gain. Objective To examine the association between AP use and glucose homeostasis… read more here.

Keywords: meta analysis; homeostasis; weight gain; glucose homeostasis ... See more keywords

Oral Targeted MXenzyme – Armed Probiotic Regulates Intestinal Redox and Microbiota Homeostasis to Synergistically Ameliorate Ulcerative Colitis

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recommendations! Published in 2025 at "Advanced Functional Materials"

DOI: 10.1002/adfm.202421680

Abstract: Ulcerative colitis (UC) leads to complex alterations in the intestinal microenvironment, with gut microbiota dysbiosis and excessive reactive oxygen species (ROS) being major drivers. Previously, microecological preparations have been used to restore intestinal homeostasis and… read more here.

Keywords: akk v2c; homeostasis; ulcerative colitis; microbiota homeostasis ... See more keywords

Melittin‐Loaded Multifunctional Nanozyme for Ulcerative Colitis Treatment via Enzyme‐Immunotherapy and Ferroptosis Inhibition

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recommendations! Published in 2025 at "Advanced Functional Materials"

DOI: 10.1002/adfm.202503374

Abstract: In ulcerative colitis (UC), oxidative stress (OS) and iron overload disrupt immune homeostasis and intestinal barrier function, exacerbating inflammation through effects on macrophages and intestinal epithelial cells (IECs). Reversing macrophage‐driven inflammation and restoring homeostasis of… read more here.

Keywords: pda mel; mel; homeostasis; ulcerative colitis ... See more keywords

Probiotic‐Inspired Nanomedicine Restores Intestinal Homeostasis in Colitis by Regulating Redox Balance, Immune Responses, and the Gut Microbiome

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recommendations! Published in 2022 at "Advanced Materials"

DOI: 10.1002/adma.202207890

Abstract: Microbiota‐based therapeutics offer innovative strategies to treat inflammatory bowel diseases (IBDs). However, the poor clinical outcome so far and the limited flexibility of the bacterial approach call for improvement. Inspired by the health benefits of… read more here.

Keywords: colitis; redox balance; gut microbiome; balance immune ... See more keywords

Single‐Atom Nanozyme with Asymmetric Electron Distribution for Tumor Catalytic Therapy by Disrupting Tumor Redox and Energy Metabolism Homeostasis

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recommendations! Published in 2022 at "Advanced Materials"

DOI: 10.1002/adma.202208512

Abstract: Nanozyme catalytic therapy triggered by tumor‐specific endogenous stimuli is an emerging tumor therapy that attracts wide attention. However, the current therapeutic efficacy of nanozyme catalytic therapy is severely limited by the catalytic efficiency of nanozymes… read more here.

Keywords: catalytic therapy; single atom; nanozyme catalytic; therapy ... See more keywords

Perturbing Organelle‐Level K+/Ca2+ Homeostasis by Nanotherapeutics for Enhancing Ion‐Mediated Cancer Immunotherapy

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recommendations! Published in 2025 at "Advanced Materials"

DOI: 10.1002/adma.202416574

Abstract: Intracellular ions are involved in numerous pivotal immune processes, but the precise regulation of these signaling ions to achieve innovative immune therapeutic strategies is still a huge challenge. Here, an ion‐mediated immunotherapy agent (IMIA) is… read more here.

Keywords: ca2 homeostasis; homeostasis; ion mediated; organelle level ... See more keywords

Homeostasis Imbalance of YY2 and YY1 Promotes Tumor Growth by Manipulating Ferroptosis.

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recommendations! Published in 2022 at "Advanced science"

DOI: 10.1002/advs.202104836

Abstract: Ferroptosis is a type of programmed cell death caused by disruption of redox homeostasis and is closely linked to amino acid metabolism. Yin Yang 2 (YY2) and its homolog Yin Yang 1 (YY1) are highly… read more here.

Keywords: tumor; ferroptosis; yy2 yy1; yy1 ... See more keywords

Sensory Nerve Maintains Intervertebral Disc Extracellular Matrix Homeostasis Via CGRP/CHSY1 Axis

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recommendations! Published in 2022 at "Advanced Science"

DOI: 10.1002/advs.202202620

Abstract: Sensory nerves are long being recognized as collecting units of various outer stimuli; recent advances indicate that the sensory nerve also plays pivotal roles in maintaining organ homeostasis. Here, this study shows that sensory nerve… read more here.

Keywords: nerve; chsy1; sensory nerve; via cgrp ... See more keywords

High‐Performance Hydrogel‐Encapsulated Engineered Exosomes for Supporting Endoplasmic Reticulum Homeostasis and Boosting Diabetic Bone Regeneration

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recommendations! Published in 2024 at "Advanced Science"

DOI: 10.1002/advs.202309491

Abstract: The regeneration of bone defects in diabetic patients still faces challenges, as the intrinsic healing process is impaired by hyperglycemia. Inspired by the discovery that the endoplasmic reticulum (ER) is in a state of excessive… read more here.

Keywords: homeostasis; endoplasmic reticulum; engineered exosomes; bone ... See more keywords

Ginsenoside Rg3 Restores Mitochondrial Cardiolipin Homeostasis via GRB2 to Prevent Parkinson's Disease

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recommendations! Published in 2024 at "Advanced Science"

DOI: 10.1002/advs.202403058

Abstract: Regulating cardiolipin to maintain mitochondrial homeostasis is a promising strategy for addressing Parkinson's disease (PD). Through a comprehensive screening and validation process involving multiple models, ginsenoside Rg3 (Rg3) as a compound capable of enhancing cardiolipin… read more here.

Keywords: ginsenoside rg3; cardiolipin; parkinson disease; homeostasis ... See more keywords

Youthful Stem Cell Microenvironments: Rejuvenating Aged Bone Repair Through Mitochondrial Homeostasis Remodeling

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recommendations! Published in 2025 at "Advanced Science"

DOI: 10.1002/advs.202409644

Abstract: Extracellular matrix (ECM) derived from mesenchymal stem cells regulates antioxidant properties and bone metabolism by providing a favorable extracellular microenvironment. However, its functional role and molecular mechanism in mitochondrial function regulation and aged bone regeneration… read more here.

Keywords: bmmscs; homeostasis; stem; bone ... See more keywords