Probiotic‐Inspired Nanomedicine Restores Intestinal Homeostasis in Colitis by Regulating Redox Balance, Immune Responses, and the Gut Microbiome
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DOI: 10.1002/adma.202207890
Abstract: Microbiota‐based therapeutics offer innovative strategies to treat inflammatory bowel diseases (IBDs). However, the poor clinical outcome so far and the limited flexibility of the bacterial approach call for improvement. Inspired by the health benefits of… read more here.
Keywords: colitis; redox balance; gut microbiome; balance immune ... See more keywords
Single‐Atom Nanozyme with Asymmetric Electron Distribution for Tumor Catalytic Therapy by Disrupting Tumor Redox and Energy Metabolism Homeostasis
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DOI: 10.1002/adma.202208512
Abstract: Nanozyme catalytic therapy triggered by tumor‐specific endogenous stimuli is an emerging tumor therapy that attracts wide attention. However, the current therapeutic efficacy of nanozyme catalytic therapy is severely limited by the catalytic efficiency of nanozymes… read more here.
Keywords: catalytic therapy; single atom; nanozyme catalytic; therapy ... See more keywords
Homeostasis Imbalance of YY2 and YY1 Promotes Tumor Growth by Manipulating Ferroptosis.
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DOI: 10.1002/advs.202104836
Abstract: Ferroptosis is a type of programmed cell death caused by disruption of redox homeostasis and is closely linked to amino acid metabolism. Yin Yang 2 (YY2) and its homolog Yin Yang 1 (YY1) are highly… read more here.
Keywords: tumor; ferroptosis; yy2 yy1; yy1 ... See more keywords
Sensory Nerve Maintains Intervertebral Disc Extracellular Matrix Homeostasis Via CGRP/CHSY1 Axis
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DOI: 10.1002/advs.202202620
Abstract: Sensory nerves are long being recognized as collecting units of various outer stimuli; recent advances indicate that the sensory nerve also plays pivotal roles in maintaining organ homeostasis. Here, this study shows that sensory nerve… read more here.
Keywords: nerve; chsy1; sensory nerve; via cgrp ... See more keywords
Modeling tensional homeostasis in multicellular clusters.
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DOI: 10.1002/cnm.2801
Abstract: Homeostasis of mechanical stress in cells, or tensional homeostasis, is essential for normal physiological function of tissues and organs and is protective against disease progression, including atherosclerosis and cancer. Recent experimental studies have shown that… read more here.
Keywords: homeostasis; tensional homeostasis; homeostasis multicellular; modeling tensional ... See more keywords
The bioelements, the elementome, and the biogeochemical niche.
Sign Up to like & getrecommendations! Published in 2019 at "Ecology"
DOI: 10.1002/ecy.2652
Abstract: Every living creature on Earth is made of atoms of the various bioelements that are harnessed in the construction of molecules, tissues, organisms, and communities, as we know them. Organisms need these bioelements in specific… read more here.
Keywords: homeostasis; biogeochemical niche; elementome biogeochemical; bioelements elementome ... See more keywords
Fibroblast‐derived IL‐33 is dispensable for lymph node homeostasis but critical for CD8 T‐cell responses to acute and chronic viral infection
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DOI: 10.1002/eji.201948413
Abstract: Upon viral infection, stressed or damaged cells can release alarmins like IL‐33 that act as endogenous danger signals alerting innate and adaptive immune cells. IL‐33 coming from nonhematopoietic cells has been identified as important factor… read more here.
Keywords: homeostasis; cd8; infection; viral infection ... See more keywords
Galectin‐9: Diverse roles in hepatic immune homeostasis and inflammation
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DOI: 10.1002/hep.29106
Abstract: Glycan‐binding proteins, which include galectins, are involved at all stages of immunity and inflammation, from initiation through resolution. Galectin‐9 (Gal‐9) is highly expressed in the liver and has a wide variety of biological functions in… read more here.
Keywords: homeostasis; galectin diverse; hepatic immune; inflammation ... See more keywords
Dissecting copper homeostasis in diabetes mellitus
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DOI: 10.1002/iub.1614
Abstract: Diabetes Mellitus (DM) is characterized by elevated blood glucose levels (hyperglycemia). It can occur due to impaired secretion or action of the hormone insulin, which is produced by pancreatic beta‐cells to promote the entry of… read more here.
Keywords: homeostasis; homeostasis diabetes; copper homeostasis; dissecting copper ... See more keywords
Lung inflammation and disease: A perspective on microbial homeostasis and metabolism
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DOI: 10.1002/iub.1969
Abstract: It is now well appreciated that the human microbiome plays a significant role in a number of processes in the body, significantly affecting its metabolic, inflammatory, and immune homeostasis. Recent research has revealed that almost… read more here.
Keywords: homeostasis; metabolism; disease; microbiome ... See more keywords
Neuropeptide Y Acts Directly on Cartilage Homeostasis and Exacerbates Progression of Osteoarthritis Through NPY2R
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DOI: 10.1002/jbmr.3991
Abstract: Neuropeptide Y (NPY) is known to regulate bone homeostasis; however, its functional role as a risk factor during osteoarthritis (OA) remains elusive. In this study, we aim to investigate the direct effect of NPY on… read more here.
Keywords: homeostasis; acts directly; cartilage homeostasis; directly cartilage ... See more keywords