Dissecting copper homeostasis in diabetes mellitus
Sign Up to like & getrecommendations! Published in 2017 at "IUBMB Life"
DOI: 10.1002/iub.1614
Abstract: Diabetes Mellitus (DM) is characterized by elevated blood glucose levels (hyperglycemia). It can occur due to impaired secretion or action of the hormone insulin, which is produced by pancreatic beta‐cells to promote the entry of… read more here.
Keywords: homeostasis; homeostasis diabetes; copper homeostasis; dissecting copper ... See more keywords
Pancreatic Pericytes in Glucose Homeostasis and Diabetes.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-11093-2_2
Abstract: Glucose homeostasis relies on tightly regulated insulin secretion from pancreatic beta-cells, and its loss in diabetes is associated with the dysfunction of these cells. Beta-cells reside in the islets of Langerhans, which are highly vascularized… read more here.
Keywords: glucose homeostasis; homeostasis diabetes; pancreatic pericytes; pericytes glucose ... See more keywords
Targeting Orphan Nuclear Receptors NR4As for Energy Homeostasis and Diabetes
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.587457
Abstract: Orphan nuclear receptors are important members of the nuclear receptor family and may regulate cell proliferation, metabolism, differentiation, and apoptosis. NR4As, a subfamily of orphan nuclear receptors, have been reported to play key roles in… read more here.
Keywords: nuclear receptors; homeostasis diabetes; energy; energy homeostasis ... See more keywords
Zinc Homeostasis in Diabetes Mellitus and Vascular Complications
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10010139
Abstract: Oxidative stress represents an impaired metabolic system that promotes damage to cells and tissues. This is the predominant factor that leads to the development and progression of diabetes and diabetic complications. Research has indicated that… read more here.
Keywords: zinc homeostasis; oxidative stress; vascular complications; zinc ... See more keywords