A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology
Sign Up to like & getrecommendations! Published in 2018 at "Nature neuroscience"
DOI: 10.1038/s41593-018-0298-7
Abstract: Excitatory neurons are preferentially impaired in early Alzheimer’s disease but the pathways contributing to their relative vulnerability remain largely unknown. Here we report that pathological tau accumulation takes place predominantly in excitatory neurons compared to… read more here.
Keywords: homeostasis signature; excitatory neurons; tau homeostasis; pathology ... See more keywords