A tRNA modification balances carbon and nitrogen metabolism by regulating phosphate homeostasis
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DOI: 10.7554/elife.44795
Abstract: Cells must appropriately sense and integrate multiple metabolic resources to commit to proliferation. Here, we report that S. cerevisiae cells regulate carbon and nitrogen metabolic homeostasis through tRNA U34-thiolation. Despite amino acid sufficiency, tRNA-thiolation deficient… read more here.
Keywords: homeostasis; trna; homeostasis trna; carbon nitrogen ... See more keywords