miR-329– and miR-495–mediated Prr7 down-regulation is required for homeostatic synaptic depression in rat hippocampal neurons
Sign Up to like & getrecommendations! Published in 2022 at "Life Science Alliance"
DOI: 10.1101/2022.03.08.483397
Abstract: In rat hippocampal neurons, miRNA-dependent regulation of the synaptic Prr7 protein is required for the homeostatic synaptic depression of excitatory synapses upstream of the CDK5-SPAR pathway. Homeostatic synaptic depression (HSD) in excitatory neurons is a… read more here.
Keywords: synaptic depression; hsd; rat hippocampal; regulation ... See more keywords
Hebbian and Homeostatic Synaptic Plasticity—Do Alterations of One Reflect Enhancement of the Other?
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DOI: 10.3389/fncel.2020.00050
Abstract: During the past 50 years, the cellular and molecular mechanisms of synaptic plasticity have been studied in great detail. A plethora of signaling pathways have been identified that account for synaptic changes based on positive… read more here.
Keywords: plasticity alterations; hebbian homeostatic; alterations one; synaptic plasticity ... See more keywords