Cyclic oligomer design with de novo αβ‐proteins
Sign Up to like & getrecommendations! Published in 2017 at "Protein Science"
DOI: 10.1002/pro.3270
Abstract: We have previously shown that monomeric globular αβ‐proteins can be designed de novo with considerable control over topology, size, and shape. In this paper, we investigate the design of cyclic homo‐oligomers from these starting points.… read more here.
Keywords: cyclic oligomer; homo oligomers; design novo; backbone ... See more keywords
Computational Design of Self-Assembling Cyclic Protein Homo-oligomers
Sign Up to like & getrecommendations! Published in 2017 at "Nature chemistry"
DOI: 10.1038/nchem.2673
Abstract: Self-assembling cyclic protein homo-oligomers play important roles in biology and the ability to generate custom homo-oligomeric structures could enable new approaches to probe biological function. Here we report a general approach to design cyclic homo-oligomers… read more here.
Keywords: protein; self assembling; homo; homo oligomers ... See more keywords
ProtCHOIR: a tool for proteome-scale generation of homo-oligomers.
Sign Up to like & getrecommendations! Published in 2021 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbab182
Abstract: The rapid developments in gene sequencing technologies achieved in the recent decades, along with the expansion of knowledge on the three-dimensional structures of proteins, have enabled the construction of proteome-scale databases of protein models such… read more here.
Keywords: homo; homo oligomers; protchoir tool; proteome scale ... See more keywords