Synthesis of C-Nor-D-homo-steroidal Alkaloids and Their Derivatives
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DOI: 10.1055/s-0036-1591965
Abstract: The C-nor-D-homo-steroidal alkaloid cyclopamine was discovered in the 1969 and in 2000 it was shown to act as an inhibitor of the hedgehog signaling (Hh) pathway, which is aberrantly activated in some tumors. Subsequently it… read more here.
Keywords: homo steroidal; homo; cyclopamine; synthesis homo ... See more keywords