Enantioselective Rhodium-Catalyzed Allylation of Aliphatic Imines: Synthesis of Chiral C-Aliphatic Homoallylic Amines.
Sign Up to like & getrecommendations! Published in 2020 at "Organic letters"
DOI: 10.1021/acs.orglett.0c02069
Abstract: Reported herein is a method for the efficient syntheses of optically active 1-alkyl homoallylic amines in yields up to 95%, 13.5:1 dr, and 98% ee under mild, aqueous reaction conditions, via the Rh-catalyzed asymmetric allylation… read more here.
Keywords: catalyzed allylation; enantioselective rhodium; homoallylic amines; rhodium catalyzed ... See more keywords
Iridium-Catalyzed Asymmetric Umpolung Allylation of N-FluorÂenyl Imines to Prepare 1,4-Disubstituted Homoallylic Amines
Sign Up to like & getrecommendations! Published in 2017 at "Synlett"
DOI: 10.1055/s-0036-1588514
Abstract: The discovery and development of an Ir-catalyzed asymmetric umpolung allylation of imines is discussed here. This method produces 1,4-disubstituted homoallylic amines, a class of compounds that are difficult to access by conventional methods. This reaction… read more here.
Keywords: catalyzed asymmetric; homoallylic amines; umpolung allylation; asymmetric umpolung ... See more keywords
Cobalt-catalyzed Synthesis of Homoallylic Amines from Imines and Terminal Alkenes
Sign Up to like & getrecommendations! Published in 2019 at "Chemistry Letters"
DOI: 10.1246/cl.190378
Abstract: Homoallylic amines are important synthetic targets in organic synthesis. Compared to other conventional allylation reactions using pre-functionalized allylic compounds, the allylation of imines usi... read more here.
Keywords: synthesis; synthesis homoallylic; amines imines; homoallylic amines ... See more keywords