The start of the Abiogenesis: Preservation of homochirality in proteins as a necessary and sufficient condition for the establishment of the metabolism.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of theoretical biology"
DOI: 10.1016/j.jtbi.2018.05.009
Abstract: Biosystems contain an almost infinite amount of vital important details, which together ensure their life. There are, however, some common structures and reactions in the systems: the homochirality of carbohydrates and proteins, the metabolism and… read more here.
Keywords: homochirality; establishment; metabolism; homochirality proteins ... See more keywords
Possible chemical and physical scenarios towards biological homochirality.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Society reviews"
DOI: 10.1039/d1cs01179k
Abstract: The single chirality of biological molecules in terrestrial biology raises more questions than certitudes about its origin. The emergence of biological homochirality (BH) and its connection with the appearance of life have elicited a large… read more here.
Keywords: homochirality; biological homochirality; life; chiral bias ... See more keywords
Perspectives on parity violation in chiral molecules: theory, spectroscopic experiment and biomolecular homochirality
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d2sc01323a
Abstract: The reflection (or ‘mirror’) symmetry of space is among the fundamental symmetries of physics. It is connected to the conservation law for the quantum number parity and a fundamental ‘non-observable’ property of space (as defined… read more here.
Keywords: homochirality; violation; physics; parity ... See more keywords
Homochirality and chiral-induced spin selectivity: A new spin on the origin of life
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2210505119
Abstract: The fundamental questions of “Where do we come from?” and “How did life begin?” date back millennia. Yet, the scientific community still seeks to understand abiogenesis, the origin of life. It is now generally agreed… read more here.
Keywords: homochirality; origin life; spin; life ... See more keywords
Duplex Formation and the Origins of Homochirality.
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DOI: 10.1089/ast.2021.0018
Abstract: The roots of biological homochirality remain unknown despite decades of study. A commonly proposed path includes an initial small enantiomeric excess that was amplified over time, but a satisfactory source of the excess and a… read more here.
Keywords: origins homochirality; formation origins; astrobiology; duplex formation ... See more keywords
Theoretical Investigation into a Possibility of Formation of Propylene Oxide Homochirality in Space
Sign Up to like & getrecommendations! Published in 2022 at "Astrobiology"
DOI: 10.1089/ast.2022.0005
Abstract: The preferential synthesis or destruction of a single enantiomer by ultraviolet circularly polarized light (UV-CPL) has been proposed as a possible triggering mechanism for the extraterrestrial origin of homochirality. Herein, we investigate the photoabsorption property… read more here.
Keywords: homochirality; propylene oxide; possibility formation; theoretical investigation ... See more keywords
The Origin of Biological Homochirality.
Sign Up to like & getrecommendations! Published in 2019 at "Cold Spring Harbor perspectives in biology"
DOI: 10.1101/cshperspect.a032540
Abstract: SUMMARYThe fact that sugars, amino acids, and the biological polymers they construct exist exclusively in one of two possible mirror-image forms has fascinated scientists and laymen alike for more than a century. Yet, it was… read more here.
Keywords: origin biological; homochirality; biological homochirality;
Homochirality through Photon-Induced Denaturing of RNA/DNA at the Origin of Life
Sign Up to like & getrecommendations! Published in 2018 at "Life"
DOI: 10.3390/life8020021
Abstract: Since a racemic mixture of chiral nucleotides frustrates the enzymeless extension of RNA and DNA, the origin of homochirality must be intimately connected with the origin of life. Homochirality theories have elected to presume abiotic… read more here.
Keywords: homochirality; dna; rna dna; induced denaturing ... See more keywords
Computing the Parameter Values for the Emergence of Homochirality in Complex Networks
Sign Up to like & getrecommendations! Published in 2019 at "Life"
DOI: 10.3390/life9030074
Abstract: The goal of our research is the development of algorithmic tools for the analysis of chemical reaction networks proposed as models of biological homochirality. We focus on two algorithmic problems: detecting whether or not a… read more here.
Keywords: values emergence; homochirality; emergence homochirality; mirror symmetry ... See more keywords
Possible Roles of Amphiphilic Molecules in the Origin of Biological Homochirality
Sign Up to like & getrecommendations! Published in 2019 at "Symmetry"
DOI: 10.3390/sym11080966
Abstract: A review. The question of homochirality is an intriguing problem in the field of chemistry, and is deeply related to the origin of life. Though amphiphiles and their supramolecular assembly have attracted less attention compared… read more here.
Keywords: amphiphilic molecules; roles amphiphilic; molecules origin; possible roles ... See more keywords
Origin of Homochirality: The Formation and Stability of Homochiral Peptides in Aqueous Prebiological Environment in the Earth's Crust
Sign Up to like & getrecommendations! Published in 2023 at "Symmetry"
DOI: 10.3390/sym15010155
Abstract: The oldest forms of living organisms on Earth are about 3.5 billion years old, and they are found in hydrothermal deposits, and it is often hypothesized that life originated there. However, hydrothermal systems with a… read more here.
Keywords: earth crust; homochirality; environment; environment earth ... See more keywords