Dithiothreitol causes toxicity in C. elegans by modulating the methionine–homocysteine cycle
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.76021
Abstract: The redox reagent dithiothreitol (DTT) causes stress in the endoplasmic reticulum (ER) by disrupting its oxidative protein folding environment, which results in the accumulation and misfolding of the newly synthesized proteins. DTT may potentially impact… read more here.
Keywords: dtt; homocysteine cycle; methionine homocysteine; toxicity ... See more keywords