Articles with "homolog" as a keyword



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Source-Sink Regulation Is Mediated by Interaction of an FT Homolog with a SWEET Protein in Potato

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Published in 2019 at "Current Biology"

DOI: 10.1016/j.cub.2019.02.018

Abstract: Potato plants form tuberous storage organs on underground modified stems called stolons. Tubers are rich in starch, proteins, and other important nutrients, making potato one of the most important staple food crops. The timing of… read more here.

Keywords: source sink; potato; mediated interaction; homolog ... See more keywords
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Src homolog and collagen homolog1 isoforms in acute and chronic liver injuries.

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Published in 2021 at "Life sciences"

DOI: 10.1016/j.lfs.2021.119302

Abstract: Src homolog and collagen homolog (SHC) proteins are adaptor proteins bound to cell surface receptors that play an important role in signal transduction and related diseases. As an important member of the SHC protein family,… read more here.

Keywords: src homolog; liver; homolog collagen; chronic liver ... See more keywords
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Improved global protein homolog detection with major gains in function identification

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Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2211823120

Abstract: Significance Homolog detection, finding similar proteins to an unknown protein, is usually the first step in understanding the role and function of that protein. However, if the identity of protein sequences between query and target… read more here.

Keywords: homolog detection; global protein; homolog; improved global ... See more keywords
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HbtR, a Heterofunctional Homolog of the Virulence Regulator TcpP, Facilitates the Transition between Symbiotic and Planktonic Lifestyles in Vibrio fischeri

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Published in 2020 at "mBio"

DOI: 10.1128/mbio.01624-20

Abstract: TcpP homologs are widespread throughout the Vibrio genus; however, the only protein in this family described thus far is a V. cholerae virulence regulator. Here, we show that HbtR, the TcpP homolog in V. fischeri,… read more here.

Keywords: fischeri; virulence regulator; light organ; regulator ... See more keywords
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Redox regulation of the yeast voltage-gated Ca2+ channel homolog Cch1p by glutathionylation of specific cysteine residues

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Published in 2017 at "Journal of Cell Science"

DOI: 10.1242/jcs.202853

Abstract: ABSTRACT Cch1p, the yeast homolog of the pore-forming subunit α1 of the mammalian voltage-gated Ca2+ channel (VGCC), is located on the plasma membrane and mediates the redox-dependent influx of Ca2+. Cch1p is known to undergo… read more here.

Keywords: glutathionylation; cch1p; yeast; activation ... See more keywords
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Chromosome separation during Drosophila male meiosis I requires separase-mediated cleavage of the homolog conjunction protein UNO

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Published in 2020 at "PLoS Genetics"

DOI: 10.1371/journal.pgen.1008928

Abstract: Regular chromosome segregation during the first meiotic division requires prior pairing of homologous chromosomes into bivalents. During canonical meiosis, linkage between homologous chromosomes is maintained until late metaphase I by chiasmata resulting from meiotic recombination… read more here.

Keywords: protein; separase mediated; meiosis; homolog conjunction ... See more keywords
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Tubulin Polymerization Promoting Protein, Ringmaker, and MAP1B Homolog Futsch Coordinate Microtubule Organization and Synaptic Growth

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Published in 2019 at "Frontiers in Cellular Neuroscience"

DOI: 10.3389/fncel.2019.00192

Abstract: Drosophila Ringmaker (Ringer) is homologous to the human Tubulin Polymerization Promoting Proteins (TPPPs) that are implicated in the stabilization and bundling of microtubules (MTs) that are particularly important for neurons and are also implicated in… read more here.

Keywords: futsch; synaptic growth; organization; homolog ... See more keywords
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C. elegans MANF Homolog Is Necessary for the Protection of Dopaminergic Neurons and ER Unfolded Protein Response

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Published in 2018 at "Frontiers in Neuroscience"

DOI: 10.3389/fnins.2018.00544

Abstract: Neurotrophic factors (NTFs) are important for the development, function, and survival of neurons in the mammalian system. Mesencephalic astrocyte-derived neurotrophic factor (MANF) and cerebral dopamine neurotrophic factor (CDNF) are two recently identified members of a… read more here.

Keywords: unfolded protein; protein response; dopaminergic neurons; elegans manf ... See more keywords
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5-Methoxyindole, a Chemical Homolog of Melatonin, Adversely Affects the Phytopathogenic Fungus Fusarium graminearum

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Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms222010991

Abstract: Fusarium graminearum is a destructive fungal pathogen that threatens the production and quality of wheat, and controlling this pathogen is a significant challenge. As the cost-effective homolog of melatonin, 5-methoxyindole showed strong activity against F.… read more here.

Keywords: graminearum; homolog melatonin; fusarium graminearum; homolog ... See more keywords
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Exploring the Role of a Novel Interleukin-17 Homolog from Invertebrate Marine Mussel Mytilus coruscus in Innate Immune Response: Is Negative Regulation by Mc-Novel_miR_145 the Key?

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Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24065928

Abstract: Interleukin-17 (IL-17) represents a class of proinflammatory cytokines involved in chronic inflammatory and degenerative disorders. Prior to this study, it was predicted that an IL-17 homolog could be targeted by Mc-novel_miR_145 to participate in the… read more here.

Keywords: mytilus coruscus; novel mir; homolog; immune response ... See more keywords
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Analysis of the expression level and methylation of tumor protein p53, phosphatase and tensin homolog and mutS homolog 2 in N-methyl-N-nitrosourea-induced thymic lymphoma in C57BL/6 mice.

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Published in 2017 at "Oncology letters"

DOI: 10.3892/ol.2017.6721

Abstract: Tumorigenesis is often caused by somatic mutation or epigenetic changes in genes that regulate aspects of cell death, proliferation and survival. Although the functions of multiple tumor suppressor genes have been well studied in isolation,… read more here.

Keywords: thymic lymphoma; expression level; homolog; tumor ... See more keywords