Multi-substrate selectivity based on key loops and non-homologous domains: new insight into ALKBH family
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DOI: 10.1007/s00018-020-03594-9
Abstract: AlkB homologs (ALKBH) are a family of specific demethylases that depend on Fe 2+ and α-ketoglutarate to catalyze demethylation on different substrates, including ssDNA, dsDNA, mRNA, tRNA, and proteins. Previous studies have made great progress… read more here.
Keywords: family; key loops; homologous domains; alkbh family ... See more keywords