Allosteric targeting of the FFA2 receptor (GPR43) restores responsiveness of desensitized human neutrophils
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DOI: 10.1002/jlb.2a0720-432r
Abstract: The G protein‐coupled free fatty acid receptor 2 (FFA2R) is highly expressed on neutrophils and was previously described to regulate neutrophil activation. Allosteric targeting of G protein‐coupled receptors (GPCRs) is increasingly explored to create distinct… read more here.
Keywords: activation; receptor; allosteric targeting; human neutrophils ... See more keywords
H7 virus-like particles assembled by hemagglutinin containing H3N2 transmembrane domain and M1 induce broad homologous and heterologous protection in mice
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DOI: 10.1016/j.vaccine.2018.07.004
Abstract: Abstract Influenza A H7N9 virus has caused five outbreak waves of human infections in China since 2013 and posed a dual challenge to public health and poultry industry. There is an urgent need to develop… read more here.
Keywords: virus like; transmembrane domain; hemagglutinin; like particles ... See more keywords
Choosing between Homologous or Heterologous COVID-19 Vaccination Regimens: A Cross-Sectional Study among the General Population in Italy
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DOI: 10.3390/ijerph19052944
Abstract: A shortage of COVID-19 vaccines and reports of side-effects led several countries to recommend a heterologous regimen for second vaccine doses. This study aimed to describe the reasons behind individuals’ choices of a homologous or… read more here.
Keywords: vaccination; cross sectional; homologous heterologous; covid vaccination ... See more keywords
Comparison of Homologous and Heterologous Booster SARS-CoV-2 Vaccination in Autoimmune Rheumatic and Musculoskeletal Patients
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DOI: 10.3390/ijms231911411
Abstract: Vaccination against SARS-CoV-2 to prevent COVID-19 is highly recommended for immunocompromised patients with autoimmune rheumatic and musculoskeletal diseases (aiRMDs). Little is known about the effect of booster vaccination or infection followed by previously completed two-dose… read more here.
Keywords: autoimmune rheumatic; vaccination; rheumatic musculoskeletal; booster ... See more keywords
Reporter Flaviviruses as Tools to Demonstrate Homologous and Heterologous Superinfection Exclusion
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DOI: 10.3390/v14071501
Abstract: Binjari virus (BinJV) is a lineage II or dual-host affiliated insect-specific flavivirus previously demonstrated as replication-deficient in vertebrate cells. Previous studies have shown that BinJV is tolerant to exchanging its structural proteins (prM-E) with pathogenic… read more here.
Keywords: heterologous superinfection; superinfection exclusion; homologous heterologous; reporter ... See more keywords
Safety Profile of Homologous and Heterologous Booster COVID-19 Vaccines in Physicians in Quito-Ecuador: A Cross-Sectional Study
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DOI: 10.3390/vaccines11030676
Abstract: More than 600 healthcare workers died due to COVID-19 infection until January 2022 in Ecuador. Even though the COVID-19 vaccines are safe, local and systemic reactions were reported among physicians. This study aims to analyze… read more here.
Keywords: heterologous booster; covid vaccines; booster; homologous heterologous ... See more keywords