Interactions of long-chain homologues of colchicine with tubulin.
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DOI: 10.1016/j.ejmech.2016.11.049
Abstract: Several colchicine analogues in which the N-acetyl residue has been replaced by aliphatic, straight-chain acyl moieties, have been synthesized. These compounds show high cytotoxic activity at the nanomolar level against the tumoral cell lines HT-29,… read more here.
Keywords: chain; colchicine; long chain; homologues colchicine ... See more keywords