On the Mechanism of Homology Search by RecA Protein Filaments.
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical journal"
DOI: 10.1016/j.bpj.2017.01.018
Abstract: Genetic stability is a key factor in maintaining, survival, and reproduction of biological cells. It relies on many processes, but one of the most important is a homologous recombination, in which the repair of breaks… read more here.
Keywords: search reca; search; mechanism homology; homology search ... See more keywords
A sensitive short read homology search tool for paired-end read sequencing data
Sign Up to like & getrecommendations! Published in 2017 at "BMC Bioinformatics"
DOI: 10.1186/s12859-017-1826-2
Abstract: BackgroundHomology search is still a significant step in functional analysis for genomic data. Profile Hidden Markov Model-based homology search has been widely used in protein domain analysis in many different species. In particular, with the… read more here.
Keywords: read; search; short pair; homology search ... See more keywords
Remote homology search with hidden Potts models
Sign Up to like & getrecommendations! Published in 2020 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1008085
Abstract: Most methods for biological sequence homology search and alignment work with primary sequence alone, neglecting higher-order correlations. Recently, statistical physics models called Potts models have been used to infer all-by-all pairwise correlations between sites in… read more here.
Keywords: potts models; hidden potts; homology; homology search ... See more keywords