Smart Alkoxyamines: A New Tool for Smart Applications.
Sign Up to like & getrecommendations! Published in 2020 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.0c00457
Abstract: ConspectusIn 1986, Rizzardo et al. discovered the nitroxide-mediated polymerization which relies on the reversibility of homolysis of the C-ON bond of alkoxyamine R1R2NOR3, a unique property of these molecules. This discovery has generated a tremendous… read more here.
Keywords: new tool; smart alkoxyamines; alkoxyamines new; bond ... See more keywords
A Comprehensive Multireference Study of Excited-State Ni-Br Bond Homolysis in (dtbbpy)NiII(aryl)(Br).
Sign Up to like & getrecommendations! Published in 2024 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.4c02572
Abstract: The mechanism of visible light-driven Ni-C(aryl) bond homolysis in (2,2'-bipyridine)NiII(aryl)(halide) complexes, which play a crucial role in metallaphotoredox catalysis for cross-coupling reactions, has been well studied. Differently, the theoretical understanding of Ni-halide bond homolysis remains… read more here.
Keywords: bond homolysis; excited state; niii aryl; homolysis ... See more keywords
Iron-Catalyzed C(sp3)-H Amination Enabled by Visible-Light β-Homolysis.
Sign Up to like & getrecommendations! Published in 2025 at "Organic letters"
DOI: 10.1021/acs.orglett.5c03480
Abstract: In this study, we developed a visible light-mediated C(sp3)-H amination strategy enabled by ligand-to-metal charge transfer (LMCT) and iron catalysis. The inexpensive Fe(NO3)3·9H2O affords a photoactive iron complex upon coordination with N-heteroaryl substrates, and the… read more here.
Keywords: sp3 amination; visible light; amination; iron catalyzed ... See more keywords
Computational Support for Phillips Catalyst Initiation via Cr–C Bond Homolysis in a Chromacyclopentane Site
Sign Up to like & getrecommendations! Published in 2018 at "ACS Catalysis"
DOI: 10.1021/acscatal.7b03724
Abstract: Using density functional theory, we examine a possible homolysis initiation mechanism for the Phillips catalyst, starting from CrII sites exposed to ethylene. Spin-crossing in an abundant quintet bis(ethylene) CrII site leads to cycloaddition to form… read more here.
Keywords: initiation; phillips catalyst; site; homolysis ... See more keywords
Radicals as Exceptional Electron-Withdrawing Groups: Nucleophilic Aromatic Substitution of Halophenols Via Homolysis-Enabled Electronic Activation.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c10296
Abstract: While heteroatom-centered radicals are understood to be highly electrophilic, their ability to serve as transient electron-withdrawing groups and facilitate polar reactions at distal sites has not been extensively developed. Here, we report a new strategy… read more here.
Keywords: electron withdrawing; homolysis; electronic activation; substitution ... See more keywords
Halogen Atom Transfer-Induced Homolysis of C-F Bonds by the Excited-State Boryl Radical.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.4c06337
Abstract: A novel reactivity toward C-F bond functionalization has been developed, which could be designated as fluorine atom transfer (FAT). A photoexcited state of an N-heterocyclic carbene-ligated boryl radical exhibits a transcendent reactivity, capable of activating… read more here.
Keywords: homolysis; state; atom transfer; boryl radical ... See more keywords
Direct observation of reversible bond homolysis by 2D EXSY NMR
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d2sc03028d
Abstract: Bond homolysis is one of the most fundamental bond cleavage mechanisms. Thus, understanding of bond homolysis influences the development of a wide range of chemistry. Photolytic bond homolysis and its reverse process have been observed… read more here.
Keywords: observation reversible; spectroscopy; direct observation; bond homolysis ... See more keywords
Pathogen Enzyme-Mediated Alkoxyamine Homolysis as a Killing Mechanism of Aspergillus fumigatus
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Fungi"
DOI: 10.3390/jof11070503
Abstract: The emergence of antifungal-resistant Aspergillus fumigatus (A. fumigatus) became a serious public health concern, underscoring the need for new effective antifungal agents. Here, we present a strategy based on the in situ generation of radical… read more here.
Keywords: pathogen enzyme; fumigatus; pathogen; enzyme mediated ... See more keywords