Homolytic aromatic substitution of acyl radicals: Oxidative coupling of 2-methylquinolines with quinoxalines
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DOI: 10.1177/17475198221126026
Abstract: Oxidative coupling of 2-methylquinolines with quinoxalines via a TBHP (t-butyl hydroperoxide) and TFA (trifluoroacetic acid) mediated Minisci reaction affords quinolin-2-yl(quinoxalin-2-yl)methanone derivatives. This approach provides a simple and efficient method to construct various acyl derivatives in… read more here.
Keywords: aromatic substitution; substitution acyl; methylquinolines quinoxalines; coupling methylquinolines ... See more keywords
Alkylation of Heteroaryl Chlorides through Homolytic Aromatic Substitution by Alkyl Radicals Derived from Alkyl Formates
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DOI: 10.1246/cl.210015
Abstract: The alkylation of heteroaryl chlorides through a homolytic aromatic substitution (HAS) mechanism was achieved by the use of alkyl formates as alkylating agents in the presence of a tert-butoxy radi... read more here.
Keywords: heteroaryl chlorides; alkyl formates; homolytic aromatic; aromatic substitution ... See more keywords