Design, synthesis, biological evaluation and molecular docking of new 1,3,4-oxadiazole homonucleosides and their double-headed analogs as antitumor agents.
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DOI: 10.1016/j.bioorg.2020.104558
Abstract: A novel series of homonucleosides and their double-headed analogs containing theophylline, 1,3,4-oxadiazole, and variant nucleobases was designed and synthesized. The new derivatives were fully characterized by HRMS, FT-IR, 1H NMR, and 13C NMR. The cytotoxic… read more here.
Keywords: headed analogs; design synthesis; homonucleosides double; cell ... See more keywords