Homophilic Interactions of Platelet F11R/JAM-A with Its Surface-Bound Counterpart Facilitate Thrombus Formation
Sign Up to like & getrecommendations! Published in 2024 at "Thrombosis and Haemostasis"
DOI: 10.1055/a-2565-9496
Abstract: Background F11Receptor/junctional adhesion molecule-A (F11R/JAM-A) is a transmembrane protein expressed in endothelial cells, epithelial cells, and in blood platelets. In blood platelets, F11R/JAM-A participates in adhesion under static conditions, suppresses the activation of the platelet… read more here.
Keywords: jam; thrombus formation; homophilic interactions; surface bound ... See more keywords
EMD originates from hyaluronan-induced homophilic interactions of CD44 variant-expressing MM cells under shear stress
Sign Up to like & getrecommendations! Published in 2022 at "Blood Advances"
DOI: 10.1182/bloodadvances.2022007291
Abstract: Key Points • Stromal cell–derived hyaluronan binds to CD44 variants on MM cells and generates cell clusters under shear stress in the bone marrow.• MM cell clusters serve as a seed of EMD and express… read more here.
Keywords: hyaluronan induced; induced homophilic; emd originates; originates hyaluronan ... See more keywords