Diastereoselective access to substituted oxetanes via hydrosilylation-iodocyclisation of homopropargylic alcohols.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc03339a
Abstract: The regio and stereoselective hydrosilylation of a variety of homopropargylic alcohols and their derivatives is described. The reaction is tolerant to a variety of sterically and electronically varied substrates, affording only the E-vinyl silane as… read more here.
Keywords: substituted oxetanes; diastereoselective access; access substituted; homopropargylic alcohols ... See more keywords
Base-controlled divergent synthesis of cyclopropyl aryl methanones from homopropargylic alcohols with DMTST
Sign Up to like & getrecommendations! Published in 2026 at "Chemical Communications"
DOI: 10.1039/d5cc05964j
Abstract: A method for synthesizing cyclopropyl aryl methanones from homopropargylic alcohols using dimethyl(methylthio)sulfonium trifluoromethanesulfonate has been developed. The reaction selectivity, governing the formation of cyclopropane or methylthio-cyclopropane architectures, is controlled by the choice of base. This… read more here.
Keywords: cyclopropyl aryl; methanones homopropargylic; base controlled; aryl methanones ... See more keywords