Engineering of Phosphoserine Aminotransferase Increases the Conversion of l-Homoserine to 4-Hydroxy-2-ketobutyrate in a Glycerol-Independent Pathway of 1,3-Propanediol Production from Glucose.
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology journal"
DOI: 10.1002/biot.201900003
Abstract: Phosphoserine aminotransferase (SerC) from Escherichia coli (E. coli) MG1655 is engineered to catalyze the deamination of homoserine to 4-hydroxy-2-ketobutyrate, a key reaction in producing 1,3-propanediol (1,3-PDO) from glucose in a novel glycerol-independent metabolic pathway. To… read more here.
Keywords: phosphoserine aminotransferase; production; phosphoserine; glycerol independent ... See more keywords
(2R)- and (2S)- 2-hydroxy- hexanoyl and octanoyl-l-homoserine lactones: New highly potent Quorum Sensing modulators with opposite activities.
Sign Up to like & getrecommendations! Published in 2020 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2020.104307
Abstract: The synthesis and the QS modulation activity of diastereoisomerically pure 2-hydroxy-N-acyl-l-homoserine lactones (2-OH-AHLs) are unveiled. (2R)- and (2S)- 2-hydroxy-N-hexanoyl-l-homoserine lactone and 2-hydroxy-N-octanoyl-l-homoserine lactone have been identified as very potent QS agonists and antagonists on the… read more here.
Keywords: quorum sensing; homoserine lactones; hexanoyl; octanoyl homoserine ... See more keywords
Metagenomic analysis of quorum sensing systems in activated sludge and membrane biofilm of a full-scale membrane bioreactor
Sign Up to like & getrecommendations! Published in 2019 at "Journal of water process engineering"
DOI: 10.1016/j.jwpe.2019.100952
Abstract: Abstract Biofouling hampers the long-lasting operation of membrane bioreactor (MBR) and quorum sensing (QS) can be applied to control biofouling. In this study, N-acyl homoserine lactones (AHLs), QS/quorum quenching (QQ) functional genes, and microbial communities… read more here.
Keywords: membrane biofilm; activated sludge; homoserine; membrane ... See more keywords
Rational Engineering of Homoserine O-Succinyltransferase from Escherichia coli for Reduced Feedback Inhibition by Methionine.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.1c07211
Abstract: Methionine is an essential amino acid in all living organisms and has been used in various industrial applications such as food and feed additives. However, inhibition of enzymes involved in methionine biosynthesis is considered to… read more here.
Keywords: reduced feedback; feedback inhibition; methionine; homoserine succinyltransferase ... See more keywords
Controlled Synthesis and Properties of Poly(l-homoserine).
Sign Up to like & getrecommendations! Published in 2023 at "ACS macro letters"
DOI: 10.1021/acsmacrolett.3c00122
Abstract: We report the preparation of a new water-soluble, nonionic homopolypeptide poly(l-homoserine) as well as poly(l-homoserine) block copolymers with controllable segment lengths. The conformational preferences of poly(l-homoserine) were also determined in both the solid state and… read more here.
Keywords: water; controlled synthesis; properties poly; homoserine ... See more keywords
YgeA is involved in L- and D-homoserine metabolism in Escherichia coli.
Sign Up to like & getrecommendations! Published in 2022 at "FEMS microbiology letters"
DOI: 10.1093/femsle/fnac096
Abstract: Non-canonical D-amino acids are involved in peptidoglycan and biofilm metabolism in bacteria. Previously, we identified amino acid racemases with broad substrate specificity, including YgeA from Escherichia coli, which strongly prefers homoserine as a substrate. In… read more here.
Keywords: metabolism; ygea deficient; escherichia coli; strain ... See more keywords
Combination of bacterial N-acyl homoserine lactones primes Arabidopsis defenses via jasmonate metabolism
Sign Up to like & getrecommendations! Published in 2023 at "Plant Physiology"
DOI: 10.1093/plphys/kiad017
Abstract: Abstract N-acyl homoserine lactones (AHLs) are important players in plant–bacteria interactions. Different AHL-producing bacteria can improve plant growth and resistance against plant pathogens. In nature, plants may host a variety of AHL-producing bacteria and frequently… read more here.
Keywords: homoserine lactones; combination; acyl homoserine; homoserine ... See more keywords
Unusual enantiomeric D,L-N-acyl homoserine lactones in Pectobacterium atrosepticum and Pseudomonas aeruginosa
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0283657
Abstract: Quorum Sensing allows bacteria to sense their population density via diffusible N-acyl homoserine lactone (N-HL) signaling molecules. Upon reaching a high enough cell density, bacteria will collectively exhibit a phenotype. Until recently, methods used for… read more here.
Keywords: homoserine lactones; pseudomonas aeruginosa; pectobacterium atrosepticum; acyl homoserine ... See more keywords
Salmonella enterica Optimizes Metabolism After Addition of Acyl-Homoserine Lactone Under Anaerobic Conditions
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2020.01459
Abstract: Acyl-homoserine lactones (AHLs) are quorum sensing (QS) signaling molecules that mediate cell-to-cell communication in Gram-negative bacteria. Salmonella does not produce AHL, however, it can recognize AHLs produced by other species through SdiA protein modulating important… read more here.
Keywords: acyl homoserine; anaerobic conditions; c12 hsl; homoserine lactone ... See more keywords