Homotaurine, a safe blood-brain barrier permeable GABAA-R-specific agonist, ameliorates disease in mouse models of multiple sclerosis
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DOI: 10.1038/s41598-018-32733-3
Abstract: There is a need for treatments that can safely promote regulatory lymphocyte responses. T cells express GABA receptors (GABAA-Rs) and GABA administration can inhibit Th1-mediated processes such as type 1 diabetes and rheumatoid arthritis in… read more here.
Keywords: mouse models; disease; homotaurine; multiple sclerosis ... See more keywords