Joined at the hip: The role of light chain complementarity determining region 2 in antibody self-association
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DOI: 10.1073/pnas.2208330119
Abstract: The amplification of weak transient protein–protein interactions to elicit robust immune responses is a recurring theme in immune processes (1) (Fig. 1). Given the often highly repetitive nature of pathogenic targets, antibodies have evolved architectures… read more here.
Keywords: self association; chain complementarity; homotypic interactions; antibody self ... See more keywords