Articles with "homozygous carriers" as a keyword



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Physical activity attenuates postprandial hyperglycaemia in homozygous TBC1D4 loss-of-function mutation carriers

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Published in 2021 at "Diabetologia"

DOI: 10.1007/s00125-021-05461-z

Abstract: The common muscle-specific TBC1D4 p.Arg684Ter loss-of-function variant defines a subtype of non-autoimmune diabetes in Arctic populations. Homozygous carriers are characterised by elevated postprandial glucose and insulin levels. Because 3.8% of the Greenlandic population are homozygous… read more here.

Keywords: medicine; homozygous carriers; activity attenuates; loss function ... See more keywords