Articles with "homozygous ccr5" as a keyword



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Generation of human induced pluripotent stem cells from individuals with a homozygous CCR5Δ32 mutation

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Published in 2019 at "Stem cell research"

DOI: 10.1016/j.scr.2019.101481

Abstract: Chemokine receptor 5 (CCR5) is the primary coreceptor for HIV entry into macrophages. Individuals with a homozygous deletion of 32 bp in the CCR5 gene (CCR5Δ32) are highly resistant to HIV infection (Samson et al.,… read more here.

Keywords: individuals homozygous; homozygous ccr5; pluripotent stem; induced pluripotent ... See more keywords