Generation of Rybp homozygous knockout murine ES cell line GIBHe001-A-1 by using CRISPR/Cas9 technology.
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DOI: 10.1016/j.scr.2019.101638
Abstract: RYBP (Ring1 and YY1 Binding Protein) is critical for pluripotency and differentiation of embryonic stem cells (ESCs). RYBP depletion disturbs both neural and myocardial differentiation of ESCs. Moreover, low level of RYBP is correlated with… read more here.
Keywords: crispr cas9; rybp homozygous; homozygous knockout; using crispr ... See more keywords