Tolerance and Pharmacokinetics of Galliprant™ Administered Orally to Collies Homozygous for MDR1-1Δ.
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DOI: 10.1111/jvp.12984
Abstract: The objectives of the study were to evaluate the pharmacokinetics and tolerance of grapiprant, a substrate of the human P-gp transporter, in collies homozygous for MDR1-1Δ when administered at the labeled dosage of 2 mg/kg once… read more here.
Keywords: tolerance pharmacokinetics; collies homozygous; homozygous mdr1; pharmacokinetics galliprant ... See more keywords
Safety of oral afoxolaner formulated with or without milbemycin oxime in homozygous MDR1‐deficient collie dogs
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DOI: 10.1111/jvp.13064
Abstract: Abstract Afoxolaner, an insecticide and acaricide compound of the isoxazoline class, is available for dogs as an oral ectoparasiticide medicine (NexGard®) and as an oral endectoparasiticide medicine in combination with milbemycin oxime (MO), a macrocyclic… read more here.
Keywords: safety; homozygous mdr1; collie dogs; afoxolaner ... See more keywords