Multiple Myeloma Staging in Real World Clinical Practice Is Suboptimal: Absence of Beta-2-Microglobulin and Serum Lactase Dehydrogenase Testing Are Limiting Factors
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DOI: 10.1182/blood-2018-99-119559
Abstract: Background: Staging systems, which help define prognosis and influence treatment decisions, for myeloma have evolved. The Durie-Salmon system (DS) was based largely on perceived myeloma cell tumor burden. In 2005, the International Staging System (ISS)… read more here.
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Leukocytosis Is Associated with End Organ Damage in Chronic Myelomonocytic Leukemia (CMML) and Can be Mitigated with Cytoreductive Therapy
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DOI: 10.1182/blood-2018-99-120184
Abstract: Introduction: CMML is a myeloid neoplasm hallmarked by cytopenias and a peripheral monocytosis. Although uniformly fatal, many patients (pts) are diagnosed incidentally and are monitored without treatment. Therapy is implemented when symptomatic cytopenias, splenomegaly, or… read more here.
Keywords: amc; speakers bureau; cmml; consultancy ... See more keywords
Efficacy and Safety of BAY 94-9027 (Damoctocog Alfa Pegol) Prophylaxis in Patients with Severe Hemophilia a and Comorbidities: A Post Hoc Analysis of PROTECT VIII Data
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DOI: 10.1182/blood-2019-128486
Abstract: Background: The availability of factor (F)VIII replacement products has dramatically improved life expectancy for patients with hemophilia A (HA). However, older patients face distinct challenges. Age-related comorbidities such as cardiovascular disease (CVD), often involving treatments… read more here.
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A Phase II Study to Assess the Sustained Response Off Treatment in Patients with ITP Receiving Eltrombopag, Who Had a Previous Insufficient Response to Corticosteroids (TAPER): A Recruitment Update
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DOI: 10.1182/blood-2020-137398
Abstract: Corticosteriods (CSs) remain the standard of care for immune thrombocytopenia (ITP); however, many patients relapse after initial treatment, and long-term CS use is associated with considerable toxicity and tolerability issues (Provan et al. Blood 2010).… read more here.
Keywords: treatment; sustained response; speakers bureau; honoraria speakers ... See more keywords
The Prognostic Significance of Minimal Residual Disease in Multiple Myeloma in the Molecular Genetic Groups Msmart 3.0
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DOI: 10.1182/blood-2020-139239
Abstract: Assessment of the role of genetic abnormalities and minimal residual disease (MRD) is an active developing area in hematology. The use of genetic methods makes it possible to predict the course of the disease and… read more here.
Keywords: mrd; months mrd; speakers bureau; mrd group ... See more keywords
Next-Generation Sequencing Targeted Chronic Lymphocytic Leukemia Panel: A Pilot Study
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DOI: 10.1182/blood-2020-139418
Abstract: Background: Rapid progress in next-generation sequencing (NGS) technologies make it possible to spell out the mutational status, the genetic and epigenetic variability of chronic lymphocytic leukemia (CLL). The identification of driver mutations allows us to… read more here.
Keywords: cll; mutational status; speakers bureau; honoraria speakers ... See more keywords
Impact of the Covid-19 Pandemic on Quality of Life of Patients with CML
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DOI: 10.1182/blood-2021-153742
Abstract: Introduction Introduction of imatinib and other tyrosine kinase inhibitors (TKIs) dramatically improved the quality of life (QoL) of patients with chronic myeloid leukemia (CML). However, the impact of Covid-19 on the QoL of patients with… read more here.
Keywords: speakers bureau; vaccination; health; honoraria speakers ... See more keywords