A representation transfer learning approach for enhanced prediction of growth hormone binding proteins
Sign Up to like & getrecommendations! Published in 2020 at "Computational biology and chemistry"
DOI: 10.1016/j.compbiolchem.2020.107274
Abstract: Growth hormone binding proteins (GHBPs) are soluble proteins that play an important role in the modulation of signaling pathways pertaining to growth hormones. GHBPs are selective and bind non-covalently with growth hormones, but their functions… read more here.
Keywords: representation transfer; binding proteins; growth hormone; growth ... See more keywords
Estradiol induces allosteric coupling and partitioning of sex-hormone-binding globulin monomers among conformational states
Sign Up to like & getrecommendations! Published in 2021 at "iScience"
DOI: 10.1016/j.isci.2021.102414
Abstract: Summary Sex-hormone-binding globulin (SHBG) regulates the transport and bioavailability of estradiol. The dynamics of estradiol's binding to SHBG are incompletely understood, although it is believed that estradiol binds to each monomer of SHBG dimer with… read more here.
Keywords: hormone; shbg; estradiol binding; sex hormone ... See more keywords
An ultrasensitive electrochemical immunosensor for detection of sex hormone binding globulin
Sign Up to like & getrecommendations! Published in 2019 at "Microchemical Journal"
DOI: 10.1016/j.microc.2019.104010
Abstract: Abstract A novel electrochemical immunosensor was fabricated for detection of polycystic ovary syndrome (PCOS) by immobilizing horseradish peroxidase (HRP) labeled sex hormone binding globulin (SHBG) antibody (Ab) onto chitosan (CHIT), copper nanoparticles (CuNPs), iron nanoparticles… read more here.
Keywords: immunosensor; electrochemical immunosensor; electrode; sex hormone ... See more keywords
Serum sex hormone-binding globulin is associated with symptomatic late-onset hypogonadism in aging rural males: a community-based study.
Sign Up to like & getrecommendations! Published in 2021 at "Sexual health"
DOI: 10.1071/sh20201
Abstract: BACKGROUND To investigate whether serum levels of sex hormone-binding globulin (SHBG) and testosterone are associated with symptomatic late-onset hypogonadism (SLOH) in middle-aged and elderly rural Chinese males. METHODS A population-based cross-sectional study was conducted in… read more here.
Keywords: late onset; binding globulin; sex hormone; symptomatic late ... See more keywords
First trimester sex hormone-binding globulin predicts gestational diabetes mellitus in a population of Nigerian women
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Obstetrics and Gynaecology"
DOI: 10.1080/01443615.2022.2114321
Abstract: Abstract There has been a steady rise in the disease burden of Gestational Diabetes Mellitus (GDM) in the sub-Saharan African region over time. Diagnostic testing for GDM is currently recommended at 24 − 28 weeks of gestation,… read more here.
Keywords: gdm; hormone binding; first trimester; gestational diabetes ... See more keywords
Nonlinear association of sex hormone-binding globulin levels and chronic kidney disease, an analysis based on the National Health and Nutrition Examination Survey (NHANES) 2013–2016
Sign Up to like & getrecommendations! Published in 2024 at "Renal Failure"
DOI: 10.1080/0886022x.2024.2409341
Abstract: Abstract Studies on the relationship between serum sex hormone-binding globulin (SHBG) levels and chronic kidney disease (CKD) remain limited and inconclusive. Therefore, this study aims to evaluate the effects of SHBG on CKD in a… read more here.
Keywords: ckd; sex hormone; hormone binding; shbg levels ... See more keywords
The association between serum sex hormone-binding globulin changes during progestin-primed ovarian stimulation and embryo outcomes: a retrospective cohort study
Sign Up to like & getrecommendations! Published in 2022 at "Gynecological Endocrinology"
DOI: 10.1080/09513590.2022.2112940
Abstract: Abstract Objective: This study is aimed to examine the associations between embryo outcomes and serum sex hormone-binding globulin (SHBG) changes during progestin-primed ovarian stimulation (PPOS) protocols in IVF/ICSI cycles. Research methods: This study included 2790… read more here.
Keywords: hormone binding; embryo outcomes; serum sex; sex hormone ... See more keywords
Sex hormone-binding globulin and thrombin generation in women using hormonal contraception
Sign Up to like & getrecommendations! Published in 2017 at "Biomarkers"
DOI: 10.1080/1354750x.2016.1204010
Abstract: Abstract Objectives: We investigated the impact of serum sex hormone-binding globulin (SHBG) on thrombin generation (TG) in women according to hormonal contraception. Patients and methods: A cross-sectional study of SHBG and TG measured via calibrated… read more here.
Keywords: contraception; thrombin generation; sex hormone; binding globulin ... See more keywords
Association between sex hormone-binding globulin and kidney function in men: results from the SPECT-China study
Sign Up to like & getrecommendations! Published in 2022 at "Chinese Medical Journal"
DOI: 10.1097/cm9.0000000000002046
Abstract: Abstract Background: The association between sex hormone-binding globulin (SHBG) and renal function has rarely been reported in men. We aimed to investigate the above association in a community-based Chinese population. Methods: A total of 5027… read more here.
Keywords: hormone binding; sex hormone; binding globulin; low egfr ... See more keywords
The causal effects of genetically predicted sex hormone-binding globulin and sarcopenia: A 2-sample Mendelian randomization study.
Sign Up to like & getrecommendations! Published in 2025 at "Medicine"
DOI: 10.1097/md.0000000000044654
Abstract: Observational studies suggest a link between sex hormone-binding globulin (SHBG) and sarcopenia, but the causal relationship is unclear. We conducted a 2-sample Mendelian randomization (MR) study using genome-wide association studies summary data to explore the… read more here.
Keywords: sex hormone; hormone binding; mendelian randomization; sarcopenia ... See more keywords
Sex differences, endogenous sex‐hormone hormones, sex‐hormone binding globulin, and exogenous disruptors in diabetes and related metabolic outcomes
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Diabetes"
DOI: 10.1111/1753-0407.12517
Abstract: In assessing clinical and pathophysiological development of type 2 diabetes (T2D), the critical role of the sex steroids axis is underappreciated, particularly concerning the sex‐specific relationships with many relevant cardiometabolic outcomes. In this issue of… read more here.
Keywords: hormones sex; sex; sex hormone; binding globulin ... See more keywords