Thyroid Hormone Disruption by Organophosphate Esters Is Mediated by Nuclear/Membrane Thyroid Hormone Receptors: In Vitro, In Vivo, and In Silico Studies.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental science & technology"
DOI: 10.1021/acs.est.1c05956
Abstract: Earlier mechanistic studies of many prohibited flame retardants (FRs) highlighted their thyroid hormone-disrupting activity through nuclear thyroid hormone receptors (nTRs), whereas some alternative FRs such as organophosphate esters (OPEs) exerted weak nTR-disrupting effects. However, an… read more here.
Keywords: hormone; organophosphate esters; hormone receptors; thyroid hormone ... See more keywords
Hormone disrupting chemicals: slow progress to regulation
Sign Up to like & getrecommendations! Published in 2018 at "British Medical Journal"
DOI: 10.1136/bmj.k1876
Abstract: Chemicals such as phthalates may harm humans but remain ubiquitous in manufactured goods. Barbara Casassus reports on what is happening in the EU read more here.
Keywords: chemicals slow; hormone disrupting; progress regulation; slow progress ... See more keywords